2-(4’-硝基苯基)-4,5-二(3’-硝基苯基)咪唑合成及机理研究  

Synthesis of 2-(p-nitrophenyl)-4,5-di(m-nitrophenyl)imidazole and study of reaction mechanism

作　　者：高妍[1] 张志强[1] 周袭非[1] 胡知之[1] 

机构地区：[1]鞍山科技大学化工学院,鞍山114002

出　　处：《化工新型材料》2005年第12期42-44,共3页New Chemical Materials

基　　金：辽宁省自然科学基金(20022165)

摘　　要：以苯偶姻为原料,经过氧化、硝化和环合加成制备了2-(4’-硝基苯基)-4,5-二(3’-硝基苯基)咪唑。对最后环合加成反应的工艺条件进行了优化并研究了其反应机理,较佳反应条件为:间二硝基苯偶酰∶对硝基苯甲醛∶醋酸铵摩尔比为1∶1.2∶14,醋酸25mL,反应时间4.5h。在此条件下,目标产物收率达85.3%。2- （p-nitrophenyl）-4,5-di（m-nitrophenyl） imidazole was synthesized from benzoin through oxidation, nitration and cycloaddition reaction. The mechanism of cycloaddition and the effect of reaction conditions has been investigated,the optimum condions were determined as follows ： m dinitrobenzil ： P-nitro benzaldehyde t ammonium acetate =1 ： 1.2 ： 14,acetic acid 25mL,reaction time 4. 5h. Under these conditions,the yield of product was 85.3%.

关 键 词：2-(4’-硝基苯基)-4 5-二(3’-硝基苯基)咪唑 环合加成 反应机理 

分 类 号：O626.23[理学—有机化学]