治疗心血管疾病药的药物利用调查  

Study on the Cardiovascular Drugs Utilization

作　　者：方娟娟 孙静 廖立新 

机构地区：[1]北医大第三临床医院药剂科,100083

出　　处：《药物流行病学杂志》1996年第2期102-104,共3页Chinese Journal of Pharmacoepidemiology

摘　　要：本文随机抽查北医大三院1994年10月出院病历345份,调查其中治疗心血管疾病药:β受体阻滞剂、钙拮抗剂、硝酸酯类、血管紧张素转化酶抑制剂(ACEI)、抗心律失常药等五类药的使用情况.采用WHO推荐的“限定日剂量(DDD)”的方法作为药物利用研究的测量单位,应用Ghodse教授建议的药物利用指数(DUI)为指标对病历进行分析.结果表明:①345份病历中109份使用治疗心血管疾病的5类药,约占31.65%.②使用的5类心血管药物有17个品种,出现频率最高的有硝酸异山梨酯(73例次)、硝苯地平(65例次)、硝酸甘油(41例次)、ACEI(29例次).③该5类心血管药物的使用与病人年龄相关.④15种药物的DUI均≤1.0,仅二种药稍>1.O提示无药物滥用情况,用药基本合理.The study was based on a survey of 345 randomly selected patients discharged from the Third Hospital of Beijing Medical University in Oct. 1994. Five drugs were covered: -a-drenergic blocking agents, calcium channel blockers , nitrates, angiotensin converting enzyme inhibitors (ACEI) > anti-arrhythmic agents. The methods of Definite Daily Dosage (DDD) recommended by WHO and Drug Utilization Index(DUI) by Prof. Ghodse were employed. The results showed that; 1) the cardiovascular drugs were used in 109 out of 345 cases, accounting for 31.65%; 2) the five classes involved 17 kinds of cardiovascular drugs. Among the 17 kinds of drugs, the most frequently used drugs included isosorbide dinitrate (73), nifedipine (65), nitro-glycerin (41) and ACEI (29); 3)the utilization of the 5 classes cardiovascular drugs was related to the ages of the patients and 4) the DUI of 15 were less than 1. 0 and DUI of 2 kinds of drugs were slightly greater than 1.0, suggesting that there was no drug abuse and the use of drugs was basically rational.

关 键 词：心血管类药物 限定日剂量 药物利用指数 

分 类 号：R972[医药卫生—药品]