宫颈上皮内瘤样变与生殖道衣原体及支原体感染  

The relationships between chlamydia or mycoplasma infection or ureaplasma urealyticum and cervical intraepithelial neoplasia

作　　者：王玫[1] 吕晓杰[2] 孙玉秀[1] 丛云凤[1] 刘亚茹[1] 刘晓霞[1] 

机构地区：[1]吉林大学第一医院,吉林长春130021 [2]吉林大学第二医院

出　　处：《中国实验诊断学》2006年第1期87-89,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨沙眼衣原体、人型支原体及解脲支原体感染与宫颈上皮内瘤样病变(CIN)发病机制的关系。方法采用聚合酶链反应法对186例CIN的宫颈分泌物进行沙眼衣原体、解脲支原体及人型支原体DNA检测。结果186例CIN宫颈分泌物检测沙眼衣原体感染率明显升高,与对照组相比差异显著(P<0.05),沙眼衣原体、人型支原体及解脲支原体混合感染率升高,与对照组相比差异显著(P<0.05);而人型支原体及解脲支原体感染两组差异无显著性(P>0.05);CIN各级感染率无明显差异。结论沙眼衣原体感染与CIN的发生可能密切相关。Objective To evaluate the relationships between Chlamydia Trachomatis（CT） or Mycoplasma Hominis（MH） or ureaplasma urealyticum（UU） infection and cervical intraepithelial neoplasia（CIN）. Methods In this assay, polymerasc chain reaction was used to examine the CT and MH and 1313 DNA in cervical secretion in 186 CIN group and 89 normal control group. Results 63 of 186（33.9% ） CIN patients with CT DNA positive. The CIN group of CT infected had a significantly higher rate than that of the normal control group（ P 〈 0.05）, The co-infection of three in CIN group also had a higher rate than that of normal control group（P 〈 0.05）. About MH and UU infection no significant difference between the CIN group and the normal control group was found（P 〉 0.05）. Conclusion CT infection may be play a important role in the pathogenesis of CIN.

关 键 词：沙眼衣原体 解脲支原体 人型支原体 宫颈上皮内瘤样病变 

分 类 号：R711.7[医药卫生—妇产科学]