盆腔炎颗粒对大鼠慢性子宫内膜炎疗效的研究  

Effects of Granule Peng Qiang Yan on Chronic Inflammation of Endometrium in Rats

作　　者：王静[1] 杨军[1] 刘超[1] 

机构地区：[1]安徽省医学科学研究所,安徽合肥230061

出　　处：《中国实验方剂学杂志》2006年第1期56-58,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:观察口服盆腔炎颗粒对实验性大鼠慢性子宫内膜炎的治疗作用。方法:采用苯酚胶浆注入大鼠子宫内致炎造模一周后,连续灌胃给药15d。给药结束取大鼠子宫进行组织形态学观察,同时采血进行免疫学指标检测。结果:盆腔炎颗粒可明显提高模型大鼠血清免疫球蛋白含量和T淋巴细胞转化率;明显改善模型大鼠子宫炎变程度,经Ridit分析,与模型对照组比较,两组差异显著。结论:盆腔炎颗粒对实验性慢性子宫内膜炎性粘连模型大鼠有较好的抗子宫粘连作用,同时提高机体免疫功能。Objectives：To observe the therapeutic effects of Granule Peng Qiang Yan on chronic inflammation of endometrium in rat＇s. Methods：The Chronic Inflammation model was induced by intrauterine injection of phenol mucilage in female rats. After intrauterine injection of one week Granule Peng Qiang Yan were orally administered daily for 15 days. The rats were sacrificed after 24 hours of last oral administration. Uterine tissue samples were taken for histological observation and the blood samples were collected for measurement of the related immunologic index. Results- It was found that Granule peng Qiang Yan increased the content of serum immunoglobulins and the transformation rate of T-lymphocytes significantly. The inflammatory reaction of endometrium in rats was effectively inhibited. Conclusion.. Granule Peng Qiang Yan possesses obvious therapeutic effects to promote immunologic function and inhibit metrosynizesis in the experimental chronic inflammation of endometrium in rats.

关 键 词：盆腔炎颗粒 慢性子宫内膜炎 抗粘连 

分 类 号：R285.5[医药卫生—中药学]