血细胞比容对创伤并发急性肺损伤患者氧代谢的影响  

Effect of hematocrit on oxygen metabolism in traumatic patients with acute lung injury

作　　者：秦宗和[1] 周英华[1] 

机构地区：[1]上海第二医科大学附属宝钢医院ICU,上海201900

出　　处：《中国急救医学》2006年第1期4-6,共3页Chinese Journal of Critical Care Medicine

摘　　要：目的研究血细胞比容(Hct)对创伤并发急性肺损伤(ALI)患者氧代谢的影响。方法对26例创伤并发ALI患者在Hct不同水平通过Swan-Ganz漂浮导管监测其氧代谢的变化情况。结果随着创伤并发ALI患者Hct的增加,血液黏稠度逐渐增加,机体氧供(DO2)逐渐增加,而氧摄取率则逐渐降低,氧耗始终处于相对稳定的水平。结论Hct的增加会引起机体氧供的增加,氧摄取率的下降,这可能是由于Hct>30%增加了血液黏稠度,导致血流缓慢,从而抑制细胞氧运转所致。Objective To investigate the effects of hematocrit on oxygen metabolism in traumatic patients with acute lung injury （ALI）. Methods The hemedynamics and the oxygen metabolism parameters of a total of 26 traumatic patients with ALl were monitored through a Swan - Ganz tube at Hct levels ranging from 25% to 50%. Results Systemic DO2 increased steadily and significantly with increased Hct, but systemic O2 extraction ratio （ERO2） decreased significantly. Systemic VO2 was not affected by the changes in Hoot. Blood viscosity increased progressively with increasing Het. Conclusions A progressive increase in Hct causes a corresponding increase in systemic I）O2, and a decrease in ERO2. Hot 〉 30% nray in fact cause a decrease in blood flow rate and increase in blood viscosity, which may inhibit cellular oxygen transfer.

关 键 词：急性肺损伤 血细胞比容 氧代谢 

分 类 号：R641[医药卫生—外科学] R563.8[医药卫生—临床医学]