9例甲型副伤寒并发严重肾损害的临床分析  

Nine patients with paratyphoid fever A complicated with severe kidney damage

作　　者：蔡丽敏[1] 颜鸣鹤 黄希田 毛文忠 李云生 林曦 

机构地区：[1]浙江大学 [2]温岭市第一人民医院感染科 [3]温岭市第一人民医院肾内科 [4]温岭市第一人民医院病理科

出　　处：《中华急诊医学杂志》2006年第1期71-73,共3页Chinese Journal of Emergency Medicine

基　　金：温岭市科技局2005年立项课题(57W05324)

摘　　要：目的探讨甲型副伤寒(简称甲副)并发严重肾损害的临床特征、早期诊断思路及治疗措施。方法回顾性总结病例资料。结果中毒、消化道症状及尿检(尿蛋白、血尿等)轻度异常出现早,并随病情进展逐渐加重,泌尿系症状及氮质血症多见于极期;4例早期经抗生素治疗者病情轻,恢复快。结论甲副可导致严重肾损害,早期症状缺乏特异性,但尿检轻度异常不能忽视,为早期诊断提供依据;早期联合使用非肾毒性抗生素是避免和减轻严重肾损害的关键。Objective To study the clinical characteristics, diagnosis, and treatment of paratyphoid fever A （fever A） complicated with severe kidney damage. Methods The data were retrospectively reviewed. Results The symptoms of poisoning and gastrointestinal symptoms as well as the slightly abnormal urinalysis （proteinufia, hematuria） appeared early, which got worse along with the progression of the disease. The symptoms of urinary system and azotemia appeared in the worst period. After treatment with antibiotic, 4 patients reovered early. Conclusion Paratyphoid fever A can cause severe kidney damage, with non-speciflc symptoms at the early stage. The seriousness of the abnormal of urine test can＇t be ignored as those provides the basis for the early diagnosis. The early use of antibiotic is the key to avoid and lessen the serverity of kidney damage.

关 键 词：甲型副伤寒 肾损害 并发症 

分 类 号：R516.3[医药卫生—内科学]