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机构地区:[1]中国中医科学院中药研究所,北京100700 [2]北京汉典中西药研究开发中心,北京100700
出 处:《中国中药杂志》2006年第2期131-133,共3页China Journal of Chinese Materia Medica
摘 要:目的:研究五指牛奶Ficus hirta的化学成分。方法:采用反复硅胶柱色谱进行分离纯化,根据理化性质和光谱数据进行结构鉴定。结果:得到10个化合物,分别为β-谷甾醇(1),豆甾醇(2),补骨脂素(3),3β-羟基豆甾-5-烯-7-酮(4),5-羟基-4′,6,7,8-四甲氧基黄酮(5),4′,5,6,7,8-五甲氧基黄酮(6),芹菜素(7),β-香树素乙酸酯(8),α-香树素乙酸酯(9),橙皮苷(10)。结论:化合物4,5,6为首次从该属植物中分离得到,其他为首次从该植物中获得。Objective: To study the chemical constituents from the roots of Ficus hirta. Method: Compounds were isolated by chromatographic techniques on silica gel and HP-20 resin columns. Their structures were elucidated by chemical and spectroscopic methods. Result: Ten compounds were identified as β-sitosterol (1), stigma.sterol (2), psoralene (3), 3β-hydroxy-stigmast-5-en-7-one (4), 5-hydroxy- 4', 6, 7, 8-tetramethoxy flavone (5), 4', 5, 6, 7, 8-pentamethoxy flavone (6), 4', 5, 7-trihydroxy-flavone (7), 3βacetoxy-β-amyrin (8), 3β-aeetoxy-α-amyrin (9) and hesperidin (10). Conclusion: The compounds 4, 5, 6 were obtained from this genus for the first time, and all the compounds were obtained from this plant for the first time.
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