危重症病人胃肠功能障碍与预后关系的临床研究  

Clinical study of relationship between gastrointestinal dysfunction and prognosis in patients with critical illness

作　　者：时兢[1] 宋秀琴[2] 陆荣国[1] 俞娅芬[2] 陈鸣宇[2] 衡军峰[1] 王烨[1] 

机构地区：[1]南京医科大学附属无锡市第一人民医院ICU,江苏无锡214002 [2]苏州大学附属无锡市第四人民医院ICU,江苏无锡214062

出　　处：《肠外与肠内营养》2006年第1期14-15,18,共3页Parenteral & Enteral Nutrition

摘　　要：目的:探讨危重症病人胃肠功能障碍与预后的关系。方法:回顾性分析300危重症病人临床资料,将其分为胃肠功能障碍组(181例)和非胃肠功能障碍组(119例)。评价胃肠功能障碍与急性生理和慢性健康(A-PACHEⅡ)评分、多器官功能障碍综合征(MODS)及预后的关系。结果:综合性重症监护病房(G ICU)内胃肠功能障碍的患病率为60.3%。胃肠功能障碍组病人APACHEⅡ评分、MODS发生率和病死率,均较非胃肠功能障碍组明显升高(P<0.05)。结论:危重症病人胃肠功能障碍提示病情严重和预后不良。Objective： To investigate the relationship between gastrointestinal dysfunction and prognosis in patients with critical illness. Methods： Three hundred patients with critical illness were retrospectively analyzed and divided into two groups ： the group of gastrointestinal dysfunction （ n = 181 ） and the group of non-gastrointestinal dysfunction （n = 119 ）. The relationship between gastrointestinal dysfunction and severity score （APACHE Ⅱ score）, incidence rate of multiple organ dysfunction syndrome （MODS） and prognosis was evaluated respectedly. Results： Morbidity of gastrointestinal dysfunction in general intensive care unit （GICU） was 60.3%. APACHE Ⅱ score, incidence rate of MODS and mortality were significantly lower in the group of gastrointestinal dysfunction than those in the group of non-gastrointestinal dysfunction （ P 〈 0.05 ）. Conclusion ： The results suggested that gastrointestinal dysfunction of patients with critical illness indicated the severity of illness and the bad prognosis.

关 键 词：胃肠功能障碍 多器官功能障碍综合征 危重症 预后 

分 类 号：R449[医药卫生—诊断学]