左冠状动脉主干狭窄患者的临床和心功能特点  

Clinical and functional features of patients with left main coronary artery stenosis

作　　者：江时森[1] 黄浙勇[1] 

机构地区：[1]南京军区总医院南京大学医学院临床学院心内科,210002

出　　处：《中国医师进修杂志（内科版）》2006年第1期18-20,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的探讨左冠状动脉主干(LM)狭窄的临床特点和心功能情况。方法分析188例经冠状动脉造影证实为LM狭窄患者及200例非LM狭窄患者的临床和心功能资料。结果(1)左主干狭窄188例,占同期冠状动脉造影确诊为冠状动脉疾病患者的5.59%。(2)LM狭窄患者均合并有危险因素,LM组患者年龄较大;LM组心绞痛的发生率高于非LM组,二组心肌梗死的发生率差异无统计学意义。(3)LM组左室射血分数低于非LM组,LM合并三支组低于单纯LM组;各组间比较,左心室舒张末压各参数差异无统计学意义。结论LM狭窄患者年龄较大,心绞痛严重;病变以轻中度狭窄多见,多发生于开口处和分叉处,常合并其他冠脉病变;左室收缩功能受损严重。Objective To describe clinical and functional features of patients with left main coronary artery （LM） stenosis. Methods Significant stenosis was defined as ≥ 50%. One hundred and eighty - right patients with LM stenosis and 200 patients with clinically suspected ooronary heart disease （CHD） without LM stenosis were enrolled. Results （1） The incidence rate of LM stenosis was 5.59%. （2） Patients with LM stenosis all had risk factors. Furthemore,featured older age, higher incidence of angina pectoris,and the same incidence of myocardial infarction history when compared with the patients without LM stenosis. （3） The left ventricular ejection fraction was lower in patients with LM stenosis than that in patients without LM stenosis,and it was lower too in patients with isolated LM stenosis than in patients with LM stenosis accompanied by triple vessel stenosis. The left ventricular end diastolic pressure showed no significant difference among various groups. Conclusion Patients with LM stenosis feature older age, severe angina pectoris. Furthermore, most of them are accompanied by other vessel lesions. Most LM stenosis are located at the ostium and the crotch of LM is presented as stenosis 〈 90% .The left ventricular systolic function in patients with LM stenosis is always impaired.

关 键 词：左主干狭窄 冠状动脉造影 左心室功能 收缩功能 

分 类 号：R654.2[医药卫生—外科学] R128[医药卫生—临床医学]