经导管动脉内溶栓治疗肢体动脉血栓  

Percutaneous transcatheter thrombolysis in the treatment of arterial thrombi in limbs.

作　　者：杨林[1] 官泳松[1] 周翔平[1] 李肖[1] 刘源[1] 贺庆[1] 

机构地区：[1]四川大学华西医院

出　　处：《四川医学》2006年第2期153-154,共2页Sichuan Medical Journal

摘　　要：目的探讨经导管动脉内溶栓治疗肢体动脉血栓的价值。方法10例患者，血管造影证实为动脉血栓阻塞后，留置导管，以微泵经导管泵入尿激酶5-10万U／h。同时静脉滴注肝素钠5000U／d，行溶栓、抗凝治疗。结果动脉完全开通，临床症状缓解7例。动脉部分开通，临床症状减轻2例，动脉完全未开通1例。总有效率90％。溶栓过程中出现出血并发症2例。结论经导管动脉内溶栓是治疗肢体动脉血栓的有效方法。Objective To evaluate the value of pencutaneous catheter-directed thrombolysis in treatment of arterial thrombi in limbs. Methods 10 patients （2 men, 8 women;age range 30-75 years, mean age 60.9±13.2 years ） with arterial thrombi in limbs were treated with percutaneous transcathcter thrombolysis in our hospital. The arteriography was employed to denote the site and extent of thrombi firstly, then urokinase was injected slowly with micropump （50000-100000U/h ）. Results In this limited series,7 patients were cured and 2 patients were improved based on angiagraphic flow restoration and significant clinical improvement in the ischemia. The total effective rate was 90% and thrombolytic failure occurred in 1 patient.Hemorrhage occurred in 2 patients.Conclusion Percutaneous catheter-directed thrombalysis is an effective method to treat arterial thrombi in limbs.

关 键 词：血栓形成 介入 尿激酶 

分 类 号：R543[医药卫生—心血管疾病]