房间隔缺损介入封堵术前后心率变异性的观察  

Observation of heart rate variability before and after transcatheter closure of atrial septal defect

作　　者：张志辉[1] 宋治远[1] 庄国强[1] 孙玉锦[1] 史光鉴[1] 

机构地区：[1]第三军医大学西南医院心血管内科重庆市介入心脏病学研究所,重庆400038

出　　处：《重庆医学》2006年第3期201-202,共2页Chongqing medicine

基　　金：西南医院临床研究资助项目(SW2004017)

摘　　要：目的通过观察房间隔缺损(ASD)介入封堵术前后心率变异性(HRV)的变化,探讨介入封堵术对ASD患者心率变异性的影响及其意义。方法分别于ASD封堵术前1d、术后第4天行24h动态心电图记录,由固定的心电分析专业人员进行人机对话校正后由电脑自动得出心率变异性结果,并进行统计学分析。结果与ASD封堵术前比较,R-R间期、SDNN及SDANN在术后均明显增高,差异有统计学意义(P<0.01);在ASD封堵器直径占房间隔最大直径70%以上的B组中,术后R-R间期、SDNN及SDANN的变化较A组更明显。结论ASD经导管封堵治疗后R-R间期明显延长,SDNN及SDANN较术前显著升高,表明ASD封堵术后HRV得到改善。Objective To discuss the change and significance of heart rate variability（HRV） before and after transcatheter closure in patients with atrial septal defect（ASD）. Methods 24h record of Holter was taken at ld before and 4d after transcatheter closure. HRV was automatically analyzed by computer and then corrected by professional electrocardiogram technician. Results RR interval, SDNN, SDANN increased significantly after transcatheter closure compared to before transcatheter closure（P〈 0.01）. In the group B of occluder diameter larger than 70 % of the longest diameter of ASD, RR interval, SDNN, SDANN increased more significantly than group A after transcatheter closure. Conclusion It indicates that RR interval, SDNN and SDANN significantly increase after transcather closure. ASD transcatheter closure can result in HRV improvement.

关 键 词：房间隔缺损 经导管封堵术 心率变异性 先天性心脏病 

分 类 号：R541.1[医药卫生—心血管疾病] R815[医药卫生—内科学]