稳定期慢性阻塞性肺疾病患者贫血原因的探讨  

Research on anemia causation of patients with stable chronic obstructive pulmonary disease

作　　者：李岱容[1] 刘金华[1] 陈涛[1] 吴金星[1] 吴亚梅[1] 

机构地区：[1]重庆医科大学附属第一医院肺科,400016

出　　处：《重庆医学》2006年第3期231-232,234,共3页Chongqing medicine

摘　　要：目的探讨稳定期慢性阻塞性肺疾病(COPD)患者贫血原因。方法选择稳定期COPD患者90例,测定其血常规、肺功能、身高和体重,并计算体重指数(BMI)。分别观察肺功能损害程度、BMI与红细胞参数的关系。并以COPD患者是否贫血分为2组,观察红细胞参数、FEV1%预计值、BMI、近1年使用抗生素次数的差异。结果稳定期COPD患者的各项红细胞参数在肺功能损害较重组与损害较轻组比较时差异无统计学意义(P>0.05),BMI低于正常组与BMI正常组比较时差异亦无统计学意义(P>0.05);贫血组的红细胞各参数及BMI均低于非贫血组,存在显著性差异。近1年因COPD加重需使用抗生素次数多于非贫血组,而两组COPD患者的FEV1%预计值差异则无统计学意义。结论结果提示反复气道感染、摄入减少、消耗增加是COPD患者贫血的重要原因。Objective To explore the anemia causation of the patients with stable chronicobstructive pulmonary disease（COPD）. Methods Ninety patients with stable COPD were involved in this study; blood routine, pulmonary function（PF） and body mass index（BMI） were measured or calculated in all cases. Two groups were formed based on PF and BMI, and the parameters of erythrocyte（PE） was compared between two groups. In addition,all of the patients were luther divided in to two groups based on whether anemia existed, and patients＇ age, FEV1/pred, BMI and antibiotic usage frequency were observed in two groups. Results The degrees of anemia non-correlatlon with patients＇ PF （P〉0.05）, but correlated with BMI （P〈0.05） and repeated airway infection （P〈0.01）. Conclusion Repeated airway infection, intake reduction and consumption increase were the main reasons to cause anemia of COPD.

关 键 词：稳定期COPD 红细胞参数 贫血 

分 类 号：R563.9[医药卫生—呼吸系统]