疏肝酶治疗病毒性肝炎临床疗效观察  

THE CLINICAL TRIAL OF SHU-GAN-MEI IN TREATMENT OF VIRAL HEPATITIS

作　　者：杨波[1] 赵敏[1] 陈京[1] 程豪为 刘欣[1] 杨来举 查世饮 熊诗松[1] 

机构地区：[1]河南省医学科学研究所

出　　处：《河南医学研究》1996年第2期151-154,共4页Henan Medical Research

摘　　要：对１４４例病毒性肝炎患者使用疏肝酶与对照药强力宁治疗进行随机、对照临床试验观察。其中９６例接受疏肝酶治疗，４８例接受强力宁治疗，均连续静滴４周。结果表明：疏肝酶具有与强力宁相同的降酶、退黄、改善肝病症状的治疗作用，旦其降低血清丙氨酸转氨酶（ＡＬＴ）和胆红素（ＳＢ）的作用优于强力宁（Ｐ＜０．０５）。总有效率为８９％，显著优于强力宁的７５％（Ｐ＜０．０５）。其不良反应如一过性白细胞减少、黄疸、腹水加重等发生率较低（为６．３％），安全性较好。We have completed a randomized,controlled trial of shu-gan-mei and qiang-li-ning in 150 patients with viral hepatitis.of these 100 cases were treated with shu-gan-mei0.75 U/d in 0.9%salt solution 200 ml,iv,gtt,qd for 28d.Another 50 patients receivedqiang-li-ning 80 ml in 10% glucose solution 250 ml,iv,gtt,qd for 28d as control.Resultsshowed that the total response rate in the treated group(89%)was better than the controlgroup(76%),P<0.05.Shu-gan-mei showed better effects in decreaxing transaminase,jaun-dice and improveing clinical symptoms,The difference between two groups was statisticallysignificant(P<0.05).Side effects of Shu-gan-mei were moderate. Some more work is neededfOr observeing further responses.

关 键 词：病毒性肝炎 疏肝酶 临床疗效 

分 类 号：R512.605[医药卫生—内科学] R977.3[医药卫生—临床医学]