汞污染区居民尿中神经递质含量分析  

THE ANALYSIS OF THE NEUROTRANSMITTER CONTENTS IN RESIDENTS,URINE FROM MERCURY POLLUTION AREA

作　　者：张毅[1] 巴月[1] 崔留欣[1] 杨建勋[1] 刘华莲[1] 杨金勋 张恩[1] 秦建学 尚卫超 杨慧银[1] 

机构地区：[1]河南医科大学环境卫生学教研室,灵宝市卫生防疫站,郑州结核病防治所

出　　处：《河南医学研究》1996年第3期253-255,共3页Henan Medical Research

摘　　要：采用冷原子吸收法分别测定了汞污染区４４名居民和对照区３７名居民体内的尿汞和发汞含量；同时采用ＯＰＴ法测定了两区受检对象体内的四种神经递质（ＮＥ、ＤＡ、５－ＨＴ及５－ＨＩＡＡ）的含量。结果发现，污染区人群体内汞负荷水平和尿中神经递质的含量均高于对照区，并均有非常显著件差异（Ｐ＜０．０１）。提示汞可以干扰神经递质的代谢过程，从而对神经功能产生影响。With selective atomic-absorption method,mercury in urine and hair were de-termined in 44 residents from environmental mercury pollution area and 37 residents from thecontrol are a;and with OPT method,four kinds of neurotransmitters(NE.DA.5-HT.5-HIAA)in urine were analysed in 81 persons from two areas.The results indicate that the con-tents of mercury and neurotransmitters are higher in persons exposured to mercury pollutionthan in control and the difference is very significant(P<0.01).The results suggest that mercury may interfere the process of metablism of neurotrans-mitters and influence the nervous functions.

关 键 词：汞 神经递质 汞中毒 

分 类 号：R595.201[医药卫生—内科学]