妊娠剧吐:一项大型队列研究中的流行病学发现  

Hyperemesis gravidarium: Epidemiologic findings from a large cohort

作　　者：Bailit .J.L. 张旸(译) 马超(校) 

机构地区：[1]Dr. J.L. Bailit, Division of Maternal FetalMedicine, Department of Obstetrics and Gynecology, Cleveland, OH, United States [2]不详

出　　处：《世界核心医学期刊文摘（妇产科学分册）》2006年第1期5-6,共2页Core Journal in Obstetrics/Gynecology

摘　　要：This study was undertaken to quantify the frequency, clinical course, charges, and outcomes of hyperemesis gravidarum. Study design: California birth certificate data linked with maternal and neonatal hospital discharge data in 1999 were used (N = 520,739). Hyperemesis was defined by ICD- 9 codes. The frequency, estimated charges, and demographic characteristics associated with hyperemesis patients were assessed. Maternal and neonatal perinatal outcomes were compared by maternal hyperemesis status. Results: Hyperemesis complicated 2,466 of 520,739 births. The average length of stay was 2.6 days and the average charge was ＄ 5,932. Singleton hyperemesis infants were smaller (3,255 vs 3,380 g; P < .0001 and more likely to be small for gestational age (29.21% vs 20.8% ; P < .0001). Conclusion: Hyperemesis occurs in 473 of 100,000 live births and is associated with significant charges. Infants of mothers with hyperemesis have lower birth weights and the mothers are more likely to have infants that are small for gestational age.Objective： This study was undertaken to quantify the frequency, clinical course, charges, and outcomes of hyperemesis gravidarum. Study design： California birth certificate data linked with maternal and neonatal hospital discharge data in 1999 were used （N = 520, 739） . Hyperemesis was defined by ICD- 9 codes. The frequency, estimated charges, and demographic characteristics associated with hyperemesis patients were assessed. Maternal and neonatal perinatal outcomes were compared by maternal hyperemesis status. Results： Hyperemesis cornplicated 2, stay was 2. 466 of 520, 739 births. The average length of 6 days and the average charge was $5, 932 Singleton hyperemesis infants were smaller （3, 255 vs 3, 380 g; P 〈. 0001 and more likely to be small for ges- tational age （29.21% vs 20. 8%; P 〈. 0001） . Conclu- sion： Hyperemesis occurs in 473 of 100, 000 live births and is associated with significant charges. Infants of mothers with hyperemesis have lower birth weights and the mothers are more likely to have infants that are small for gestational age.

关 键 词：妊娠剧吐 流行病学 队列研究 新生儿出生体重 ICD-9编码 小于胎龄儿 平均费用 发生频率 加利福尼亚 人口统计学 

分 类 号：R714.241[医药卫生—妇产科学] R563.1[医药卫生—临床医学]