国产牛颈静脉带瓣管道重建右室流出道临床应用  

Reconstruction of right ventricular outflow tract with bovine jugular vein valved conduit: a preliminary clinical report

作　　者：胡盛寿[1] 李守军[1] 宋云虎[1] 宋学营[2] 张浩[1] 王欣[1] 周建业[2] 

机构地区：[1]中国医学科学院 中国协和医科大学心血管病研究所 阜外心血管病医院心外科,北京100037 [2]卫生部心血管病再生医学研究重点实验室

出　　处：《中华胸心血管外科杂志》2005年第6期328-330,共3页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：本课题受科技部中小企业基金;国家杰出青年基金资助(30125039)

摘　　要：目的总结国产牛颈静脉带瓣管道在右室流出道重建手术中的应用和术后早期临床随访结果。方法 2004年2月至2005年3月,14例病人(男6例,女8例;年龄5个月-22岁;体重8-40 kg) 使用了完整牛颈静脉带瓣管道重建右室流出道。记录术后并发症,术后1个月用心脏超声对移植的牛颈静脉进行功能评价。结果住院期间均无栓塞等带瓣管道相关并发症发生,恢复顺利,出院。术后1 个月超声检查示重建的右室流出道通畅,4例移植管道存在轻度瓣膜反流。结论国产牛颈静脉带瓣管道易于获取,型号较齐全,移植后早期临床疗效满意,可作为一种右室流出道重建的替代材料,但其中、远期疗效仍须持续随访观察。Objective To summarize the experience in application of the bovine jugular vein valved conduct in right ventricular outflow tract （ROVT） reconstruction. Methods Totally 14 patients [6 male, （6.3 ± 5.4） years old] underwent ROVT reconstruction from February 2004 to March 2005 was recorded, and the function of the implanted bovine jugular vein valved conduit was evaluated by Doppler echecardiography one month later after operation. Results There was no perioperative morbidity related to the bovine jugular vein valved conduit. 14 patients were discharged well. One month after operation, echocardiography showed that reconstructed ROVT was patent, and only four implanted conduits had mild regurgition. Conclusion The bovine jugular vein valved conduit provides the favorable hemadynamic performance and thus could be an excellent substitute for the homograft in the reconstruction of ROVT. The mid- and long-term outcomes required further study.

关 键 词：室性流出道阻塞 生物假体 心脏外科手术 牛颈静脉带瓣管道 右室流出道重建 管道重建 临床应用 国产 术后并发症 早期临床 

分 类 号：R654[医药卫生—外科学]