同种异体原位心脏移植长期生存40例  

Long-term outcomes of orthotopic heart transplantation: a clinical analysis of 40 cases

作　　者：崔广晖[1] 廖崇先[1] 廖东山[1] 单忠贵[1] 范钦明[1] 万连壮[1] 刘波[1] 

机构地区：[1]福建医科大学附属协和医院心脏外科

出　　处：《中华胸心血管外科杂志》2005年第5期266-267,共2页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：目的探讨心脏移植术后长期生存病例的诊治经验和体会.方法对40例终末期扩张型心肌病病人施行同种原位心脏移植术,39例采用经典式,1例为全心脏原位移植.结果手术均顺利,生存时间8～112个月,平均62个月;生活质量均良好,能从事正常的工作和劳动,心功能0～I级;术后并发症以肺部感染和心律失常常见.结论选择合适的受者、良好的心肌保护是手术成功的关键,术后排斥反应和其他并发症的预防和处理是心脏移植成功的保证.Objective To explore the experience of long-term outcomes of orthotopic heart transplantation. Methods From Aug. 1995 to Dec. 21304, 40 patients with end-stage dilatation cardiomyopathy, 36 males and 4 females, aged 13 - 60 years underwent orthotopie heart transplantation （OHT） , 39 standard styles and 1 total style. Results 40 eases were all sueeessful treated. The survival time is from 8 to 112 months with heart funetien of 0-Ⅰ degree. All cases are in good quality of live and enjoy normal entertainments and work. Pulmonary infection and cardiac arrhythmia are the most common complications but they did not degrade the result after proper treatments. Conclusion Heart transplantation is an effective treatment for patients with end-stage heart diseases, Appropriate selections of recipients with low pulmonary vascular resistance, satisfactory myocardial preservation are the key points to success. The precautions and prompt treatments to the postoperative complications are guarantee for the ultimate results of heart transplantations.

关 键 词：心脏移植 移植物排斥 心脏移植/副作用 长期存活患者 同种异体原位心脏移植 长期生存 同种原位心脏移植术 终末期扩张型心肌病 全心脏原位移植 术后并发症 

分 类 号：R654.2[医药卫生—外科学] R733.71[医药卫生—临床医学]