动态监测CA_(125)EMAb对子宫动脉栓塞术治疗子宫腺肌病的疗效评价  

Serum CA_(125) and EMAb in evaluating the efficiancy of UAE in the treatment of adenomyosis

作　　者：禤庆山[1] 刘浪[1] 李莉[1] 朱康顺[2] 姜在波[2] 

机构地区：[1]广州市妇婴医院,广东广州510180 [2]中山大学附属第三医院,广东广州510630

出　　处：《中国实用妇科与产科杂志》2006年第2期118-120,共3页Chinese Journal of Practical Gynecology and Obstetrics

摘　　要：目的采用血清CA125、子宫内膜抗体(EMAb)动态监测,评价子宫动脉栓塞术(UAE)治疗子宫腺肌病的疗效。方法2002年3月至2004年3月对就诊于广州市妇婴医院、中山大学附属第三医院的86例确诊为子宫腺肌病患者,在UAE术前及术后连续动态监测血清CA125、EMAb之变化。结果血清CA125水平在UAE后第4周开始下降至(89±11.3)kU/L,和术前(128±44.3)kU/L比较,差异有显著性意义(P<0.05);术后CA125稳定下降,至18个月降至正常水平(<35kU/L);血清EMAb术前52例阳性,第2个月开始下降,和术前比较术后EMAb阳性率差异有显著性意义(P<0.05)。结论血清CA125、EMAb动态监测UAE治疗子宫腺肌病的疗效,其方法简单且具有临床实用意义。Objective To evaluate the efficiency of uterine arterial embolization（UAE） in treatment of adenomyosis by detecting serum CA125 and EMAb. Methods In 84 patients admitted to Guangzhou Maternal and Infant Hospital and the Third Affiliated Hospital, Sun-Yet Sen University from March 2002 to March 2004 , serum CA125 and EMAb were analyzed during different stages of pre-operation and after UAE. Results After 4 weeks＇s treatment of UAE, the concentration of CA125 in serum was reduced from （ 128±44. 32） kU/L to （89 ±11.8） kU/L, decreasing to normal at eighteen months after UAE, The positive rate of EMAh was decreased from 52 eases to 38 cases in two months after UAE. Conelusion Serum CA125 and EMAb may be a valuable and feasible index for evaluating the treatment efficiency of adenomyosis.

关 键 词：子宫内膜异位症 子宫动脉栓塞术 子宫腺肌病 CA125 子宫内膜抗体 

分 类 号：R71[医药卫生—妇产科学]