玉树高原17～24岁青年性激素测定  

THE LEVEL OF SEX HORMONE AND CORTISOL IN42YOUNGS AT 3700m HIGH ALTITUDE

作　　者：张鸿顺 苏宏运 师成杰[1] 孙骥[1] 赵方萍[1] 圈启芳[1] 张德才[1] 韩永伟[1] 高芬[1] 王克华[1] 

机构地区：[1]玉树州慢性病院,青海医学院附属医院,玉树州医院

出　　处：《高原医学杂志》1996年第2期29-31,共3页Journal of High Altitude Medicine

摘　　要：深入了解性激素在“高红症”发病中的作用和位置，对海拔３７００ｍ地区即玉树结古４２铭１７～２４岁健康青年，血清Ｔ、Ｅ２、ＦＳＨ、ＬＨ、Ｈｙｄｒｏｃｏｒｔｉｓｏｎｅ用ＲＩＡ作了检测。选择海拔２２６０ｍ西宁地区８０例１７～２４岁健康青年作对照组。测定数据两地男女分别对照作出Ｐ值。结果提示，玉树青年的性激素和皮质醇血清浓度明显高于西宁地区青年。如Ｔ（μｇ／Ｌ）：玉树青年男：１１２．６６±６７．１２，西宁青年男：６４．６７±５４．８７（Ｐ＜０．０１），玉树女：１２．２９±５．６２，西宁女：８．４０±２．５６（Ｐ＜０．０１）。Ｔ能增加ＥＰ的生成，还能直接促进骨髓制造红细胞，还与ＰＧＥ有协同作用。说明在高原（山）缺氧环境，机体内首先发生变化在“高红症”发病中起主要作用是Ｔ、ＥＰ是继发的。o study the effects of high altitude on sex hormone and cortisol of youngs.The serum speci-mens from 42 healthy youngs ,Mage 17～24 years,residing at 3 700m Yushu altitude were assayedfor the concentrations of T,E2,FSH,LH,PRL and cortisol using RIA,The results were comparedwith control group consisted of 80 youngs in Xining area of 2 260m.The results showed that theconcentration of sex hormone and cortisol of 3 700m yotings were significantly higher than thoseof Xining(P<0.05～0.01),The above findings suggested that the sex hormone and cortisol mayplay a role in the adaptation ofhumanbody to hypoxia and in the pathogenesis of high altitudedisease.

关 键 词：性激素 高山病 

分 类 号：R594.301[医药卫生—内科学]