急性一氧化碳中毒时的心功能损害  

Injuring of cardiac function in acute carbon monoxide poisoning patients

作　　者：连雪[1] 姚依群 高春锦[1] 葛环[1] 关雨章[1] 

机构地区：[1]首都医科大学附属北京红十字朝阳医院,北京军区总医院内科

出　　处：《中国介入心脏病学杂志》1996年第2期89-90,共2页Chinese Journal of Interventional Cardiology

摘　　要：３０例急性ＣＯ中毒患者，在应用２ＡＴＡ高压氧治疗前和治疗后即时观察心肌酶和超声心动图测定心功能。结果发现：ＣＯ中毒可致心肌损伤，心肌酶谱有明显的改变，其中ＣＫ－ＭＢ为６８．２±５１．４，ｖｓ３６．４±６２．２，Ｐ＜０．０１；α－ＨＢＤ为２９３．５±１８．５，ｖｓ２６６．６±１６３．７，Ｐ＜０．０２。超声心动图提示Ｃ０中毒主要影响心肌的收缩功能，ＥＦ为５２．６±５．３，ｖｓ６４．６±７．２，Ｐ＜０．００１；ＳＶ为０．０３９±０．０１２，ｖｓ０．１０５５±０．０１１，Ｐ＜０．００１；ＣＯ为３．９±０．９，ｖｓ４．５±０．８，Ｐ＜０．０５。舒张功能的影响变化不大（Ａ／Ｅ），Ｐ＞０．０５．提示在救治ＣＯ中毒的过程中，不可忽视对心脏功能的关注。cases of acute carbon monoxide poisoning were observed the myocardial enzyme and the function of heart by ultrasound before and immediatly after the treatment of hyperbaric oxygen. The result showed that the poisoning could cause myocardium injury, The enzyme of myocardium have had a obvious change,the CK-MB were 68. 2±51.4 vs 36.4±62. 2 IU,P<0.01; a-HBD were 293. 5±185. 5 vs 266.6 ±163.7,P<0.02 respectively. The function of myocardial contractility were affected measured by ultra sound. The valure of EF were 52.6±5.3% vs 646±7.2%,P<0. 001; SV were 0.039±0.012 vs 0.055±0.011,P<0.001 and CO were 3.9±0.9L/mine vs 4.5±0.8L/mine,P<0. 05 respectively. The function of myocardial diastole had a little changes (A/E),P>0.05. This report revealed that we shouldn't neglect the condition of heart in rescuing the acute carbon monoxide poisoning patients.

关 键 词：一氧化碳中毒 病理 心脏功能损害 

分 类 号：R595.102[医药卫生—内科学]