Effect of liniment levamisole on cellular immune functions of patients with chronic hepatitis B  

作　　者：Ke-Xia Wang Li-Hua Zhang Jiang-Long Peng Yong Liang Xue-Feng Wang Hui Zhi Xiang-Xia Wang Huan-Xiong Geng 

机构地区：[1]Department of Pathogenic Biology,School of Medicine, Anhui University of Science and Technology,Huainan 232001, Anhui Province, China [2]Huainan Railway Central Hospital, Huainan 232001, Anhui Province, China

出　　处：《World Journal of Gastroenterology》2005年第45期7208-7210,共3页世界胃肠病学杂志（英文版）

摘　　要：AIM: To explore the effects of liniment levamisole on cellular immune functions of patients with chronic hepatitis B. METHODS: The levels of T lymphocyte subsets and mlL-2R in peripheral blood mononuclear cells (PBMCs) were measured by biotin-streptavidin (BSA) technique in patients with chronic hepatitis B before and after the treatment with liniment levamisole. RESULTS: After one course of treatment with liniment levamisole, the levels of CD3+, CD4+, and the ratio of CD4+/CD8+ increased as compared to those before the treatment but the level of CD8+ decreased. The total expression level of mIL-2R in PBMCs increased before and after the treatment with liniment levamisole. CONCLUSION: Liniment levamisole may reinforce cellular immune functions of patients with chronic hepatitis B.AIM： To explore the effects of liniment levamisole on cellular immune functions of patients with chronic hepatitis B. METHODS： The levels of T lymphocyte subsets and mlL-2R in peripheral blood mononuclear cells （PBMCs） were measured by biotin-streptavidin （BSA） technique in patients with chronic hepatitis B before and after the treatment with liniment levamisole. RESULTS： After one course of treatment with liniment levamisole, the levels of CD3＋, CD4＋, and the ratio of CD4＋/CD8＋ increased as compared to those before the treatment but the level of CD8＋ decreased. The total expression level of mIL-2R in PBMCs increased before and after the treatment with liniment levamisole. CONCLUSION： Liniment levamisole may reinforce cellular immune functions of patients with chronic hepatitis B.

关 键 词：Liniment levamisole  Chronic hepatitis B Cellular immune function T lymphocyte subsets MIL-2R 

分 类 号：R512.62[医药卫生—内科学]