115例无症状乙肝病毒携带者肝活检病理分析  

Pathological Analysis of liver Biopsies in 115 Patients with Chronic Asymptomatic Carrier

作　　者：金巧菲[1] 刘惠敏[1] 李冰如[1] 

机构地区：[1]浙江省杭州市第六人民医院,310014

出　　处：《医学研究杂志》2006年第1期42-44,共3页Journal of Medical Research

摘　　要：目的分析无症状乙肝病毒携带者（AsC）肝组织病理特征，有助于正确诊断与治疗。方法对115例临床诊断AsC进行乙肝血清学标志、肝功能、血清HBV-DNA检测及肝活组织病理和免疫组化检查。结果在115例AsC中肝组织无明显病理变化者（G0S0）10例，占8．7％；表现为慢性肝炎34例，占29．6％，其中G0～1S0～1、G2S2和G3S3～4分别为24例、5例和5例；肝硬化2例，占1．7％。免疫组化检测HBsAg＆及HBcAg均阳性者71例，占66．96％，仅HBsAg阳性者44例，占33．04％。结论肝组织病理及免疫组化检测有助于AsC的明确诊断，并对AsC是否治疗或制定治疗方案有指导意义。Objective To analyze the pathological features of Liver in chronic asymptomatic carrier （AsC） and to diagnose and treat AsC correctly. Methods 115 patients with AsC were examined with serological markers of Bhepatitis, liver function serum, HBV-DNA level, liver biopsy and immunohistochemistry. Results Of 115 patients with AsC, there were 8.7% patients with invisibly pathological lesions of hepatic tissue （C0S0）, 29.6% patients with chronic hepatitis, 1.7% patients with cirrhosis. Through immunohistochemistry HBsAg and HBcAg test, there were 66.96% patients with HBsAg （＋） and HBcAg （＋）, 33.04% patients with single HBsAg （＋）. Conclusions Liver biopsy and immunohistochemistry can help to correct diagnose. It has important directional significance to heat AsC and establish treatment project of AsC.

关 键 词：无症状乙肝病毒携带者 免疫组织化学 肝活检 病理分析 病理特征 

分 类 号：R512.62[医药卫生—内科学]