Approaches to functional genomics in filamentous fungi  

作　　者：Richard J Weld Kim M Plummer Margaret A Carpenter Hayley J Ridgway 

机构地区：[1]National Centre for Advanced Bio-Protection Technologies, PO Box 84, Lincoln University, Canterbury 8150, New Zealand [2]LaTrobe University, Melbourne 3086, Australia

出　　处：《Cell Research》2006年第1期31-44,共14页细胞研究（英文版）

摘　　要：The study of gene function in filamentous fungi is a field of research that has made great advances in very recent years. A number of transformation and gene manipulation strategies have been developed and applied to a diverse and rapidly expanding list of economically important filamentous fungi and oomycetes. With the significant number of fungal genomes now sequenced or being sequenced, functional genomics promises to uncover a great deal of new information in coming years. This review discusses recent advances that have been made in examining gene function in filamentous fungi and describes the advantages and limitations of the different approaches.

关 键 词：functional genomics gene replacement filamentous fungi homologous recombination RNAI gene silencing OOMYCETES 

分 类 号：R378[医药卫生—病原生物学]