补肾密骨片结合经皮自体骨髓移植治疗兔桡骨骨折延迟愈合  

Treatment of rabbit's radius delayed union by Chinese traditional medicine and bone marrow transplantation

作　　者：吕建元[1] 张征石[1] 王根福[1] 徐峰[1] 

机构地区：[1]江苏昆山市中医院骨科,215300

出　　处：《中国矫形外科杂志》2006年第2期128-129,i0003,共3页Orthopedic Journal of China

摘　　要：[目的]观察口服补肾密骨片结合经皮自体骨髓移植对骨折延迟愈合的治疗作用及机制。[方法]预制新西兰大耳白兔骨延迟愈合模型,将75只兔随机分为3组:A组20只,饲料中加入补肾密骨片,骨延迟愈合区注入自体红骨髓2m l;B组20只,饲料中加入补肾密骨片,骨延迟愈合区不注入自体红骨髓;C组20只,饲料中不加补肾密骨片,骨延迟愈合区注入自体红骨髓:D组15只,造成骨延迟愈合模型后,饲料中不加补肾密骨片,骨延迟愈合区不注入自体红骨髓。治疗后4、8、12周分别行大体观察、组织学、碱性磷酸酶及X线片检查。[结果]大体标本肉眼观察、病理组织学检查、碱性磷酸酶及放射学检查均显示A组愈合时间较B、C、D组早,且愈合率明显高于B、C、D组。[结论]口服补肾密骨片结合经皮自体骨髓移植是治疗骨折延迟愈合的一种有效方法。[Objective] To explore the effects of Chinese traditional medicine and bone marrow transplantation （ BMT ） on delayed union. [ Method] The model of delayed union in rabbit＇s radius was made and divided into 4 gronps. Group A, 20 rabbits treated with Chinese traditional medicine and red marrow 2 ml; Group B, 20 rabbits treated with Chinese traditional medicine; Group C, 20 rabbits treated with red marrow; Group D, 15 rabbits treated with nothing. Histology , alkaline phosphates and x-ray were observed in the 4th , 8th and 12th weeks after treating. [ Result] Histology, alkaline phosphates and x-ray reveals that group A healed earlier than group B, C and D. At the same time, the rate of healing of group A was higher than others. [Conclusion] The treatment of delayed union by Chinese traditional medicine and bone marrow transplantation is an effective mean.

关 键 词：中药 中医治疗 骨髓 延迟愈合 

分 类 号：R687.3[医药卫生—骨科学]