周围神经端侧吻合后靶肌肉及其运动终板的形态学研究  

An experiment study of target muscle and moter endplate on peripheral nerve end-to-side neurorrhaphy

作　　者：杨家辉[1] 洪光祥[1] 王发斌[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院手外科,武汉430022

出　　处：《中国矫形外科杂志》2006年第2期130-131,i0004,共3页Orthopedic Journal of China

摘　　要：[目的]研究周围神经端侧吻合后靶肌肉及其运动终板的形态,为端侧吻合的应用提供进一步的形态学依据。[方法]W istar大白鼠26只,随机分实验组和对照组,每组13只,实验组右侧腓总神经切断后,近端反转结扎,远端与胫神经外膜开窗处行端侧吻合,对照组右侧腓总神经切断后,两端均反转结扎,两组动物左侧作正常对照,不作处理。术后3个月,行双侧腓总神经、胫前肌组织学检查,胫前肌湿重测定,运动终板检查。[结果]实验侧胫前肌结构清晰,肌纤维较粗大,运动终板面积大,结构清晰,着色深,接近正常侧。实验侧与对照侧的胫前肌肌湿重比、肌纤维截面积比、运动终板的面积比和着色比具有极显著性差异(P<0.01)。[结论]神经端侧吻合能保护靶肌肉及其运动终板。[ Objective] To study the effect of End-to-side neurorrhaphy for protection target muscle. [ Method] Twenty-six wistar rats were divided into two groups, with 13 in each group, peroneal nerve was transacted on the right side of all the animals, in one group, the proximal end of peroneal nerve was turned back and ligated, the distal end was sutured to the side of tibial nerve with perineurial window, in allother group,both ends of the transacted peroneal nerve were turned back and ligated as eontrast, no operation was done on the left side. Three months after operation,the peroneal nerve and the tibial muscle were taken for histologic exmination, and the muscle＇s wet weight was examed.[Result] Significant difference was seen between the two groups in the muscle wet weight, the musele fiber cross sectional area, the motet endplate area and color （ P 〈0. 01 ）. [ Conclusion] End-to-side neurorrhaphy can protect target muscle.

关 键 词：周围神经 端侧吻合 肌肉 运动终板 

分 类 号：R651.3[医药卫生—外科学]