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作 者:邱东鹰[1] 胡予[1] 陆健[2] 蔡映云[1] 吴琳[1] 朱继珩[1]
机构地区:[1]复旦大学附属中山医院老年病科,上海200032 [2]第二军医大学卫生勤务学系卫生统计学教研室,上海200433
出 处:《第二军医大学学报》2006年第1期58-61,共4页Academic Journal of Second Military Medical University
摘 要:目的:确定老年人人体测量指数与糖尿病或糖耐量异常(DM/IGT)之间的关系。方法:对537例(男性416例,女性121俐)参加健康体检的上海城市老年人(年龄60~85岁)进行调查,分析体质量指数(BMI)、腰围(WC)和腰臀围比值(WHR)分别与DM/IGT之间的关系;运用logisitc回归分析,受试者工作特性(ROC)曲线下面积(AUC)判断各人体测量指数对DM/IGT的预测价值。结果:(1)除女性WHR值外,本组老年男性和女性中具有DM/IGT者人体测量指数BMI、WC和WHR均高于非DM/IGT者,P〈0.05;同样,具有高BMI(≥25kg/m^2)、WC(≥90cm)和WHR(≥0.9)的DM/IGT发生率均分别大于低BMI、WC和WHR组。P〈0.05或P〈0.01。(2)在调整了年龄、活动强度和糖尿病家族史的影响后,对BMI、WC和WHR这3个因素与DM/IGT的关系进行logistic逐步回归分析,结果表明WHR和BMI分别是本组老年男性和女性DM/IGT的主要危险因素(P=0.0004,P=0.0002),ROC曲线分析表明老年男性WHR的AUC最大(P〈0.05),老年女性BMI的AUC最大(P〈0.05)。结论:在老年人群中肥胖与DM/IGT有相关性,WHR和BMI是较好的简易预测指标,在老年男女人群中分别测量WHR和BMI可以较好地预测DM/IGT的发生。Objective:To study the relationship between anthropometric indices and type 2 diabetes mellitus/impaired glucose tolerance(DM/IGT) in the elderly. Methods: This research included 5,37 people (416 males and 121 females, aged 65 85 years) undergoing medical examination in Shanghai in 2004. The body mass index (BMI), waist to hip ratio (WHR) and waist circumference (WC) were measured and their relationship with DM/IGT was analyzed. Logistic regression analysis and area un der curve (AUC) of receiver-operating characteristic (ROC) were used to study the predictive value of BMI,WHR and WC. Resuits: Except for the WHR in females,BMI, WC and WHR were higher in all subjects with DM/IGT than those without DM/ IGT. The prevalences of DM/IGT in all subjects with high BMI (≥25 kg/m^2 ), WC(≥90 cm) and WHR (≥0.9) were also significantly higher than those with low BMI, WC and WHR, except for that of the WHR in females. After adjusted by age, physical activity and the family history of DM, multiple logistic regression analysis indicated that WHR was the most important predictive factor for IGT/DM in males and the same was true for BMI in females. ROC analysis showed that the AUC of WHR was the highest in the males and of BMI in the females. Conclusiona Obesity is correlated with DM/IGT in the elderly. WHR and BMI are satisfactory predictive indicators and have higher predictive accuracy for DM/IGT in elderly males and females, respectively.
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