胰岛素样激素3与睾丸引带发育和睾丸下降  

Relationship Between Insulin Like Hormone 3 and Testicular Descent and Development

作　　者：谢肖俊[1] 蒋学武[1] 

机构地区：[1]汕头大学医学院第二附属医院小儿外科,广东汕头515041

出　　处：《中华男科学杂志》2006年第1期68-70,共3页National Journal of Andrology

基　　金：广东省自然科学基金(010438);广东省科技攻关项目(C31302)

摘　　要：睾丸下降是生殖系统发育过程中的重要阶段,其机制尚未阐明。睾丸引带发育与睾丸下降关系密切。睾丸下降不全常常伴随睾丸引带发育异常,它们除了可引起隐睾和睾丸发育不良等疾病外,还是生殖系统先天畸形以及以后生殖功能、性功能异常和高比例生殖系统肿瘤发生的原因。胰岛素样激素3是近年来倍受关注的影响睾丸引带发育和睾丸下降的重要因素,本文就相关进展进行综述。Testicular descent is an essential step in the course of reproductive system development. The mechanisms involved in the regulation of testis descent is not distinct. Gubernaculum has a very close relationship with testis descent. Maldescent of testis can cause abnormities of genital system such as testicular undescent （cryptorchidism） , dysplasia, tumor, infertility and low sexuality. Recently insulin like hormone 3 is a hotspot of concerning affecting gubernacular development and testicular descent. This article briefly reviews the advances in these aspects.

关 键 词：睾丸下降 胰岛素样激素3 睾丸引带 富含亮氨酸的孤儿G蛋白偶连受体8 外源性雌激素 

分 类 号：R726.92[医药卫生—儿科]