大脑胶质瘤DTT初步研究  

Preliminary study of cerebral gliomas using diffusion tensor tracking of MRI

作　　者：何光武[1] 项华[1] 何江波[1] 成中意[1] 徐建荪[1] 汪守中[1] 沈天真[2] 陈星荣[2] 

机构地区：[1]上海市第一人民医院宝山分院放射科,上海200940 [2]上海复旦大学附属华山医院,上海200040

出　　处：《医学影像学杂志》2006年第1期32-35,共4页Journal of Medical Imaging

摘　　要：目的:评价磁共振弥散张量纤维束成像技术在大脑胶质瘤所导致的大脑白质纤维异常改变中的价值。方法:分别对15例大脑胶质瘤患者进行弥散张量成像,对所获得的数据进行弥散张量纤维束成像,获得FA图、DEC图和DTT图,观察不同病变所引起的白质纤维束的改变情况。结果:15个病变累及的白质纤维束有弓状纤维、上纵束、内囊、上额枕束和胼胝体。白质纤维束的异常改变有2个类型:破坏+浸润5例、破坏+移位10例。结论:弥散张量纤维束成像可以显示颅内肿瘤所造成的白质纤维的异常改变,立体显示肿瘤与白质纤维束之间的关系,有利于肿瘤手术方案的制定和病人预后的预测。Objective：To evaluate the usefulness of diffusion tensor tracking in abnormal cerebral white matter induced by cerebral gliomas.Methods：To study 15 patients （7men,8 women;age range,25 - 77 years; mean age 50.0 years） using diffusion tensor. FA, DEC and DTT maps were obtained in all of 15 patients to observe abnormality of the cerebral white matter. Results：Cerebral white matter fibers including arcuate fibers, superior longitudinal fascieulus, internal capsule, superior fronto-oceipital fascieulus and corpus caUosum were involved. Abnormality of the cerebral white matter was classified into two types： disruption ＋ infiltration （5 cases）, disruption ＋ displacement infiltration （ 10 eases）. Conclusion： Diffusion tensor tracking showed the abnormality of the cerebral white matter, and allowed for visualization of cerebral white matter three dimensionally . It was found to be beneficial in the surgical planning or prognosticating the prognosis of patient.

关 键 词：胶质瘤 弥散张量纤维束成像 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.41[医药卫生—诊断学]