实时三维超声心动图定量评价左心室容积及射血分数  

Quantification of Left Ventricular Volumes and Ejection Fraction Using Real-Time Three-Dimensional Echocardiography

作　　者：张嬿[1] 唐红[1] 宋彬[2] 饶莉[1] 彭瑛[1] 吴进[1] 黄鹤[1] 

机构地区：[1]四川大学华西医院心内科,成都市610041 [2]四川大学华西医院放射科,成都市610041

出　　处：《中国超声医学杂志》2006年第2期102-104,共3页Chinese Journal of Ultrasound in Medicine

基　　金：四川省应用基础研究项目(No.04JY029-002-4);科技攻关项目(No.04SG022-016-03)资助

摘　　要：目的 探讨实时三维超声心动图（RT-3DE）定量评价左心室容积及射血分数的可行性及准确性。方法 以心脏核磁共振（cMRI）为参考标准，应用RT-3DE测量31例健康志愿者左心室舒张末期容积（LVEDV）、收缩末期容积（LVESV）、每搏量（SV）及射血分数（EF）。结果 （1）30例志愿者获得了清晰内膜边界的三维图像和CMRI图像，RT-3DE图像采集及分析时间明显短于CMRI；（2）RT-3DE测量所得LVEDV、LVESV、SV、EF与CMRI具有良好的相关性，r分别为0．946、0．939、0．950、0．947（P均〈0．001），LVEDV、LVESV、SV测值较CMRI偏小（P均〈0．001），EF测值二者间差异无显著性意义（P〉0．05）；（3）RT-3DE测值观察者内及观察者间均具有良好的一致性，r值0．903～0．947。结论 RT-3DE是一种定量评价左心室功能的准确、可靠的新技术，必将在心血管疾病诊断、治疗及随访中发挥作用。Objective Compared with cardiac magnetic resonance imaging （CMRI）, to assess the feasibility and accuracy of real-time three-dimensional echocardiography （RT-3DE） in quantifying left ventricular （LV） volumes and ejection fraction （EF） . Methods 31 healthy volunteers without cardiovascular diseases were investigated. Left ventricular end-diastolic volume （LVEDV）, end-systolic volume （ESV）, stroke volume （SV） and EF were obtained by RT-3DE and CMRI independently and blinded to each other. Results ①Acquisition of RT-3DE and CMRI datasets with good endocardium image was feasible in all except 1 volunteer. The durations of a complete RT-3DE data acquisition and analysis were much shorter than CMRI. ② LVEDV, LVESV. SV and EF obtained by RT-3DE correlated highly with CMRI （r=0. 946, 0. 939. 0. 950. 0. 947）, however, LV volumes were underestimated by RT- 3DE compared with CMRI （P= 0. 000） . The difference for EF was not significant between the two methods （P= 0. 250）. ③ For RT-3DE, intra- and inter-observer variability were acceptable, and repeatability was excellent, r value between 0. 903 and 0. 947. Conclusions RT-3DE allows accurate determination of left ventricular function. Its feasibility and accuracy suggests applicability of the method for the patients with cardiovascular diseases.

关 键 词：实时三维超声心动图 左心室功能 核磁共振 

分 类 号：R445.1[医药卫生—影像医学与核医学]