山西大同盆地地方性砷中毒病区饮用水的水砷价态暴露研究  

Studies on exposure status of water-arsenic valence state of inhabitants in endemic arsenism diseased areas of Datong Basin of Shanxi

作　　者：李军[1] 程晓天[1] 王正辉[1] 温新平[1] 韩凌凌[1] 桑志萍[1] 张杰[1] 段虎顺[1] 梁彬峰[1] 高建国[1] 

机构地区：[1]山西省地方病防治研究所,临汾041000

出　　处：《中国地方病学杂志》2006年第1期64-66,共3页Chinese Jouranl of Endemiology

基　　金：山西省卫生厅科技攻关项目(200430)

摘　　要：目的掌握大同盆地地方性砷中毒(地砷病)病区饮用水的水砷价态分布情况及其与病情的关系。方法对地砷病患者和对照者的生活饮用水进行采样,用氢化物发生-原子荧光法(HG-AFS)进行检验,SPSS10.0forWindows软件进行统计处理数据。结果大同盆地砷超标水样(>0.05mg/L)中,3价砷(As3+)占总砷(As)的比值为52.1%;As3+/总As比值,组间比较,差异有统计学意义(χ2=22.4,P<0.01),并且As3+与5价砷(As5+)比值的比较,差异有统计学意义(χ2=26.19,P<0.01);随着病情的加重,As3+与As5+的比值也在增加。结论大同盆地地砷病病区中水砷价态分布以As3+为主,地砷病病情与水体中As3+的所含比例呈正相关关系,今后在分析水含砷量时,应该摸清水砷价态的分布情况。Objective To investigate the distribution of water-arsenic valence state and its relationship with the disease state in endemic arsenism diseased areas of Datong Basin. Methods The drinking water of patients with endemic arsenism and the control group were sampled and determined by hydrogenation-atomic fluorescence （HG-AFS） method. The data were analyzed by SPSS10.0 for windows. Results As^3＋/As ratio was 52.1% in water sample with arsenic 0.05 mg/L exceeding the standard. The As^3＋/As ratio varied significantly in the differently diseased groups and the control group （X^2 = 22.4,P 〈 0.01）. The As^3＋/As^5＋ ratio varied significantly in the four groups （X^2 = 26.19,P 〈 0.01）, tending to increase along with the severity of the disease. Conclusions The most frequently seen water-arsenic valence state in drinking-water is As^3＋ in endemic arsenism areas in Datong Basin. The disease severity of endemic arsenism is related to As^3＋. The distribution of water-arsenic valence state should be mastered when the arsenic content of drinking water is determined.

关 键 词：砷化物 价态 中毒 地方病 

分 类 号：R599[医药卫生—内科学]