声学定量技术评价充血性心衰患者左室收缩、舒张功能的改变  

Evaluating left ventricular function in congestive heart failure before and after treatment by acoustic quantification

作　　者：徐冬梅[1] 张梅[2] 范崇伦[3] 姜洪菊 

机构地区：[1]济南市第三人民医院心内科,山东济南250101 [2]山东大学齐鲁医院心内科,山东济南250012 [3]济南市中心医院呼吸内科,山东济南250013 [4]济南市铁路医院心内科,山东济南250001

出　　处：《中国临床医学影像杂志》2006年第2期79-81,共3页Journal of China Clinic Medical Imaging

摘　　要：目的:采用声学定量技术观察充血性心力衰竭(心衰)患者治疗前后左室收缩、舒张功能的改变。方法:34例心衰患者为患者组(NYHA心功能III～IV级),给予常规抗心衰药物治疗。采用声学定量技术测量左室舒张末容积(EDV)、左室收缩末容积(ESV)、左室射血分数(EF)、左室峰值排空率(PER)、左室峰值快速充盈率(PRFR)、左室峰值心房充盈率(PAFR)、左室峰值快速充盈率与左室峰值心房充盈率之比(PRFRPAFR)。并以34例正常人为对照组。结果:患者组治疗前与正常组比较EDV、ESV、PAFR和PRFR明显增大(P<0.001、P<0.001、P<0.001和P<0.05),EF和PER明显减低(P<0.001和P<0.05),而PRFRPAFR无明显差异(P>0.05)。患者组治疗后与治疗前比较ESV、EDV和PAFR明显减小(P值均<0.001),EF和PER明显提高(P值均<0.001),PRFR和PRFRPAFR变化不大(P值均>0.05)。结论:声学定量技术有助于评价心衰患者的左室收缩功能,对于晚期心衰患者左室舒张功能的评价有一定局限性。Objective： To evaluate left ventricular systolic and diastolic function before and after treatment by acoustic quantification（AQ）. Methods： Thirty-four normal subjects were selected as control group, 34 consecutive patients with a clinical diagnosis of congestive heart failure were studied by echocardiography. Left ventricle end diastolic volume（EDV）, end systolic volume（ESV）, ejection fraction（EF）, peak ejection rate（PER）, peak rapid filling rate（PRFR） and peak atrium filling rate （PAFR） were also measured, PRFR/PAFR were calculated. Results： Compared with healthy controls, EDV, ESV, PRFR and PAFR had significantly increased（P〈0.001, P〈0.001, P〈0.001 and P〈0.05 respectively）, EF and PER significantly decreased（P〈 0.001 and P〈0.05 respectively）, PRFR/PAFR had no significant differences. ESV, EDV and PAFR had significantly decreased （P〈0.001）, EF and PER significantly increased（P〈0.001）, PRFR and PRFR/PAFR had no significant differences after treatment （P〉0.05）. Conclusions： AQ is helpful to evaluate left ventricular systolic function, while evaluating left ventricular diastolic function of heart failure patients in late phase, AQ is limited.

关 键 词：心力衰竭 充血性 心室功能 左 超声检查 多普勒 彩色 

分 类 号：R541.6[医药卫生—心血管疾病] R445.1[医药卫生—内科学]