大脑中动脉阻断对大鼠软脑膜微血管管径及血流速度的影响  

Effects of MCAO on Pial Microvascular Diameter and Velocity in Rats

作　　者：皇甫秋霞[1] 王春海[2] 殷镜海[2] 王世军[3] 

机构地区：[1]济南市第一人民医院,山东济南250011 [2]山东中医药大学附属医院,山东济南250011 [3]山东中医药大学,山东济南250014

出　　处：《生物医学工程研究》2005年第1期32-34,共3页Journal Of Biomedical Engineering Research

基　　金：山东省自然科学基金资助项目 (Y2 0 0 3C0 3)

摘　　要：应用闭合式颅骨开窗法观察大鼠大脑中动脉阻断(MCAO)后软脑膜微血管的改变。结果显示,MCAO后微动脉之间的吻合支发生严重的痉挛,而内外两端却均明显扩张,血液倒流,但速度较慢。微静脉明显扩张,血流速度变慢。末梢动脉收缩。The change of the pial microvascular diameter and velocity after MCAO, was observed with close cranial window method. The results showed that after MCAO the anastomosis between the arterioles contracted severely, while the two ends of the arterioles dilated obviously, blood flowed backwards and slowly. The venules were dilated remarkably and the velocity decreased. The end artery contracted and the blood flow slowed down even stopped.

关 键 词：软脑膜 微循环 大脑中动脉阻断 疾病模型 动物 

分 类 号：R318[医药卫生—生物医学工程]