三种不同方法用于紧急避孕的临床观察  

Three Different Approaches for Emergent Contraception

作　　者：邵欣胤[1] 李金彪[1] 吕玉才[1] 李凤[1] 刘芳英[1] 

机构地区：[1]山东省莱芜市计划生育指导中心,271100

出　　处：《中国计划生育学杂志》2006年第1期51-53,共3页Chinese Journal of Family Planning

基　　金：莱芜市2004年度科技计划项目(2004-19)

摘　　要：目的:观察三种方法用于紧急避孕的临床效果。方法:选择接收无保护性生活或避孕失败72小时内要求紧急避孕的健康育龄妇女354例。组Ⅰ(119例),单次口服米非司酮25mg(25mg/片);组Ⅱ(120例),左炔诺酮首次口服0.75mg(0.75mg/片),间隔12小时再服0.75mg;组Ⅲ(115例):放置含铜IUD。以服药或放置IUD后月经来潮为成功标准,以Dixon表格计算避孕有效率。结果:三组共有3例失败,均显著低于预期妊娠数(10.945,9.516,8.461)(P<0.05);避孕有效率分别为81.7%、89.5%、100%。对下次月经影响均较轻微(P>0.05),组Ⅰ副反应发生率明显低于组Ⅱ(P<0.01)。结论:三种方法用于紧急避孕安全、有效、简便。Objective： To evaluate the effectiveness of three kinds of approaches for emergent contraception. Methods： 354 healthy women who experienced unprotected sexual intercourse or failed contraception wthin 72 hours and asked for emergent contraception were divided into three groups. 119 Women in group I took a single dose of 25 mg （25 mg/tab） mifepristone. 120 cases in group Ⅱ took 0.75 mg （0.75 mg/tab） LNG and took the same dose at twelfth hour. 115 cases in group Ⅲ were inserted intrauterine device （IUD）. The contraceptive effective rate was calculated by Dixon table, according to standard of the menstruation after treatment. Results： There were 3 failed cases in three groups. The effective rates were 81.7 %, 89. 5% and 100% , respectively. Three approaches had less impact on next menses （P 〉 0.05 ）. The incidence of side effects in the group I was less than that in goup Ⅱ （P 〈0. 01 ） Conclusion： Three methods are effective, safe.

关 键 词：米非司酮 左炔诺酮 含铜IUD 紧急避孕 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]