韭子增强非特异性免疫和体液免疫作用的实验研究  

An experimental study on effect of Semen Allii Tuberosi on non-specific and humoral immunity

作　　者：于艳[1] 

机构地区：[1]佳木斯大学免疫教研室,黑龙江佳木斯154007

出　　处：《黑龙江医药科学》2006年第1期19-20,共2页Heilongjiang Medicine and Pharmacy

基　　金：佳木斯大学研究生创新科研项目;项目编号:YJSCX2005-003JD

摘　　要：目的:研究中药韭子对机体非特异性免疫作用和体液免疫作用的影响。方法:建立环磷酰胺所致免疫低下动物模型,采用中性红法检测小鼠腹腔巨噬细胞的吞噬功能,从而研究对非特异性免疫功能的影响;用溶血空斑形成细胞测定法研究对体液免疫功能的影响。结果:韭子可有效地纠正免疫功能低下,显著提高巨噬细胞的吞噬功能以及使抗体生成细胞数增多,使两者恢复至正常水平。结论:韭子可有效地恢复和增强免疫功能低下小鼠的非特异性免疫和体液免疫功能。Objective： To study the immunoregulatory effects of Semen Allii Tuberosi （SAT） on nonspecific and humoral immunity. Methods： Immunosuppressive animal model was established by cyclophosphamide（CY）. We detected the phagocytic function of peritoneal macrophage by using the neutral red method to study the effect on non-specific immunity, and we investigated the effect on humoral immunity with haemolysis plaque forming cell test. Results： SAT could efficiently correct immunodefieiency, enhance phagocytic function of macrophage and increase the number of antibody-producing cells, enabling both immune functions to return to their normal levels. Conclusion： SAT can recover both non-specific and humoral immunity of mice with immunodeficiency.

关 键 词：韭子 免疫功能低下 非特异性免疫 体液免疲 

分 类 号：R392.1[医药卫生—免疫学]