乙酰乙醛缩二甲醇的合成  

The Synthesis of Acetylacetaldehyde Dimethyl Acetal

作　　者：吕德刚 张雷 于巨青 

机构地区：[1]民生药业集团绍兴医药有限公司,浙江绍兴312071

出　　处：《化工中间体》2006年第2期8-9,25,共3页

摘　　要：介绍了适合工业化的乙酰乙醛缩二甲醇合成路线。丙酮、甲醇钠与甲酸甲酯反应得乙酰基乙烯醇钠,再与硫酸氢甲酯反应得到目标产物,收率可达71.8%。The synthetic method of acetylacetaldehyde dimethyl acetal suitable for the industrialization was introduced. The title compound was prepared from monomethyl sulfate and sodium acetyl ethenoxide, which was obtained from the reaction of acetone, sodium methoxide and methyl formate. The overall yield was 71.8%.

关 键 词：乙酰乙醛缩二甲醇 4 4-二甲氧基-2-丁酮 合成 

分 类 号：TQ203.3[化学工程—有机化工]