药用植物提取物抗烟草花叶病毒活性的研究  

Antiviral effect of medicinal plant extracts on tobacco mosaic virus

作　　者：沈建国[1] 谢荔岩[1] 吴祖建[1] 谢联辉[1] 林奇英[1] 

机构地区：[1]生物农药与化学生物学教育部重点实验室,福建农林大学植物病毒研究所,福建福州350002

出　　处：《中草药》2006年第2期259-261,共3页Chinese Traditional and Herbal Drugs

基　　金：福建省科技厅重点资助项目(99-Z-193);福建省教育厅项目(K04037)

摘　　要：目的研究我国传统药用植物抗烟草花叶病毒(tobacco m osa ic v irus,TM V)的作用,为从植物中开发抗病毒类生物农药提供依据。方法采用局部枯斑法和叶碟法对我国78科162种药用植物提取物的抗TM V侵染和增殖作用进行测定。结果在10 m g/mL水平下,19种植物提取物可有效抑制TM V侵染,9种植物提取物有明显抑制TM V增殖作用。结论大多数药用植物提取物具有一定抗TM V侵染活性,仅少数药用植物提取物有较好的抗TM V增殖作用。Objective To study antiviral activities of medicinal plant extracts against tobacco mosaic virus （TMV） and provide basis for exploitation of bio-pesticides from plant resource. Methods Using local lesion and leaf discs assay, extracts from 162 medicinal plant species belonging to 78 families in China were screened for antiviral activity against TMV. Results At a concentration of 10 mg/mL, extracts of 19 plant species could effectively inhibit TMV infection; nine plant extracts significantly inhibited the multiplication of TMV in infected leaf discs. Conclusion Most of the plant extracts exhibits certain antiviral activity of inhibiting TMV infection, but only a few have inhibitory effect on TMV multiplication.

关 键 词：药用植物 烟草花叶病毒 抗病毒活性 

分 类 号：R282.2[医药卫生—中药学]