阻塞性睡眠呼吸暂停低通气综合征120例临床分析  

Obstructive Sleep Apnea-hypopnea Syndrome: A Review of Clinical Manifestations and Diagnosis in One Hundred and Twenty Patients

作　　者：卜小宁[1] 郭兮恒[1] 王辰[1] 刘莉[1] 吴晓涛[1] 

机构地区：[1]首都医科大学附属北京朝阳医院北京呼吸疾病研究所

出　　处：《首都医科大学学报》2006年第1期81-83,共3页Journal of Capital Medical University

摘　　要：目的总结120例阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的临床资料,以期提高对OSAHS的诊治水平。方法回顾性分析北京朝阳医院120例OSAHS患者的诊治资料。结果患者就诊多是经他人提醒或是由初诊医师发现其有与睡眠紊乱有关的主诉,提示有睡眠呼吸暂停或夜间低氧血症的可能。较常见的临床症状是习惯性打鼾且鼾声不规律,27%的患者有睡眠时憋醒史。59%患者体质量指数〔体质量(kg)/身高2(m2)〕>25,Epworth嗜睡程度问卷评分为4.7±2.3。多导睡眠监测示中重度患者占70%。81.7%的患者可接受无创正压通气治疗,且经治疗后血氧饱和度均有不同程度的提高。结论多数患者在来睡眠实验室就诊以前,对睡眠紊乱情况缺乏认识。对前来就诊的患者,要进行认真的病史询问和细致的查体,并进行多导睡眠监测,以帮助诊断。无创正压通气治疗可以有效改善患者的睡眠和纠正缺氧。Objective The aims of the study were to characterize the clinical manifestations and data of laboratory tests in 120 patients with obstructive sleep apnea-hypopnea syndrome （OSAHS）, and then to improve the diagnosis and treatment of OSAHS. Methods A retrospective review was carried out in 120 patients with the diagnosis of OSAHS. Results The most common cause for these patients paying their first visits to doctors is sleep disturbance, which was initially found by spouse or friends, indicating the possibility of OSAHS and hypoxia. The most common symptoms were customary snoring and the rounds of snoring were irregular, 27 % of the patients felt suffocated during sleeping. The body mass index were over 25 in 59% of the patients, the score of Epworth scale were 4.7 ±2.3. 700/6 of the patients was diagnosed as having moderate-severe degree of OSAHS. Non-invasive positive pressure ventilation therapy was used in 81.7% of the patients. Conclusion Most patients did not pay enough attention to the catent sleep disorders, we should inquire and check patients carefully. The diagnosis was made by polysomnography, Non-invasive positive pressure ventilation therapy has an immediate effect on improving the sleep architecture and increasing hypoxemia.

关 键 词：睡眠呼吸暂停 临床分析 

分 类 号：R563.8[医药卫生—呼吸系统]