对羟基苯甲酸丁酯的微波辐射合成法研究  

Synthesis of butyl p-hydroxy benzoate under microwave irradiation

作　　者：李敏谊[1] 汤悦荣[1] 

机构地区：[1]广东药学院药科学院,广东广州510240

出　　处：《应用化工》2006年第2期128-129,共2页Applied Chemical Industry

摘　　要：对羟基苯甲酸与正丁醇在对甲苯磺酸催化下,微波辐射法合成对羟基苯甲酸丁酯。考察了酯化反应的各种影响因素,优化的反应条件为:n(对羟基苯甲酸)∶n(正丁醇)=1∶2,微波辐射功率500 W,微波辐射时间30 m in,对羟基苯甲酸丁酯产率为97%。Butyl p-hydroxy benzoate was synthesized by the reaction of p-hydroxy benzoic acid with butyl alcohol in the presence of p-methyl benzene sulfonic acid under microwave irradiation, and the influencing factors of reaction were investigated. The optimum conditions were determined as follows ： the mole ratio of p-hydroxy benzoic acid to butanol was 1：2 ,microwave irradiation power was 500 W and the reaction time was 30min, the yield of butyl p-hydroxy benzoate was 97%.

关 键 词：对羟基苯甲酸丁酯 微波辐射 酯化 

分 类 号：O621.25[理学—有机化学]