脑电双频指数指导气管拔管的临床应用  被引量:23

Application of bispectral index in evaluating the indications of extubation

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作  者:史东平[1] 杨跃武[2] 封卫征[1] 杭燕南[1] 

机构地区:[1]上海第二医科大学附属仁济医院嘉定分院麻醉科,201800 [2]上海第二医科大学附属仁济医院麻醉科

出  处:《临床麻醉学杂志》2006年第2期90-92,共3页Journal of Clinical Anesthesiology

摘  要:目的 观察脑电双频指数(BIS)监测丙泊酚镇静状态下拔除气管导管时患者的血液动力学变化,以选择最佳拔管时机。方法选择全麻患者120例,根据年龄分为青壮年组(A组,20~50岁)和老年组(B组,65~85岁),每组60例,每组再随机分为观察组(A1、B1组)和对照组(Az、B2组)。观察组术毕泵注丙泊酚,维持围拔管期患者BIS在60~80,观察并记录各组吸痰及拔管时MAP、HR,呛咳反应,清醒时间,术后有无记忆;对照组术毕不用丙泊酚。结果与同年龄的对照组相比,上述指标差异均有显著意义(P〈0.05或P〈0.01)。观察组血液动力学稳定,呛咳等反应轻微,而对照组则表现较为剧烈。结论 丙泊酚镇静时,将BIS维持在70±5范围内拔管较为适宜,可有效抑制吸痰和拔管所致的心血管反应及心理伤害,BIS可以作为在镇静状态下拔除气管导管的参考指标。Objective To evaluate the significance of BIS monitoring as a extubation sedation level during propofol infusion. Methods Sixty adults (20-50y) and 60 elderly (65-85y) were randomly derided equally into four groups with 30 cases each. The patients in propofol groups were given propofol infusion keeping BIS 60-80 till extubation, and in control groups were not given any drugs during extubation. Mean artery pressure (MAP), heart rate (HR), cough reaction, recovery time and postoperative memory were recorded at aspiration and extubation. Results The differences in above records were all significant between two propofol groups and two control groups. Conclusions The BIS level of 70±5 is a proper sedation level for extubation.

关 键 词:脑电双频指数 拔管时机 血液动力学 丙泊酚 

分 类 号:R614[医药卫生—麻醉学]

 

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