非淋菌性尿道炎患者沙眼衣原体检测和支原体的药物敏感性分析  

Detection of Chlamydia Trachomatis and Drug Sensitivity of Mycoplasma among Outpatients of the Nongonococcal Urethritis

作　　者：粟盛梅[1] 余敏君[1] 尹卫国[1] 曾铁兵[1] 唐双阳[1] 占利生[1] 

机构地区：[1]南华大学病原生物研究所,湖南衡阳421001

出　　处：《美国中华临床医学杂志》2006年第1期69-71,共3页American Journal of Chinese Clinical Medicine

摘　　要：目的了解衡阳地区非淋菌性尿道炎患者沙眼衣原体（CT）、解脲脲原体（Uu）和人型支原体（Mh）感染情况压支原体药物敏感性，为临床治疗提供参考依据。方法沙眼衣原体的检测采用PCR法，支原体压药敏试验采用本室研制的支原体分离、鉴定、药敏试剂盒。结果631例非淋菌性尿道炎（NGU）患者几种病原体的感染率分别为CT20．9％．Uu38．7％，Mh5．1％，CT＋Uu5．4％，CT＋Mh1．7％，Uu＋Mh4．0％，CT＋Uu＋Mh1.4％。Uu和Mh对9种抗生素敏感性最高的是克拉霉素，其次分别是交沙霉素和司帕沙星，耐药性最高的是罗红霉素，其次是氧氟沙星。结论CT和Uu是非淋菌性尿道炎的重要病原体，建议本地区支原体感染应首选克拉霉素进行抗感染治疗。Objective To study the infection rates of chlamydia trachomatis （CT）, Ureaplasma urealyticum （Uu）, M,hominis （Mh） and the drug sensitivity of ureaphsma urealyticum and M. hominis, and to provide the basis to use the antibiotic reasonably for clinical treatment. Methods Chlamydia trachomatis was tested by polymerase chain reaction （PCR） assays, Mycoplasma and drug sensitivity were tested by culture. Results Tho positive rate of CT, Uu, Mh, CT＋Uu, CT＋Mh, Uu＋Mh, CT＋Uu＋Mh were20.9%, 38,7%, 5.1%, 5.4%, 1.7%, 4.0%, 1.4%, respectively. Clarithromycin showed the most sensitive against ureaplasma urealyticum and M.hominis, followed by josamycin and sparfloxacin, Roxithromycin showed a highly resistant in drug sensitivity, followed by ofloxacin. Conclusions Chlamydia trachomatis and ureaplasma urealyticum are the important pathogens of the nongonococcal urethfitis. The results indicate that clarithromycin is the drug of choice for the treatment of mycoplasma infection in Hengyang area.

关 键 词：非淋菌性尿道炎 沙眼衣原体 药敏试验 解脲脲原体 人型支原体 抗生素 

分 类 号：R696[医药卫生—泌尿科学]