多普勒组织成像技术对高血压患者血压正常子女左心室舒张功能的评价  

Assessment of diastolic function of left ventricle in normotensive offspring of hypertensive parents with Doppler tissue imaging

作　　者：孔爱丽[1] 张玉东[1] 孙志丹[2] 

机构地区：[1]锦州医学院附属第一医院心内科,辽宁省锦州市121000 [2]锦州医学院附属第一医院超声科,辽宁省锦州市121000

出　　处：《中国临床康复》2006年第8期16-18,共3页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:探讨多普勒组织成像技术对高血压患者血压正常子女左心室舒张功能的评估价值。方法:选择2004-06/2005-06在锦州医学院附属第一医院心脏超声室就诊的血压正常者100名,年龄15～40岁,均自愿参加观察。按家族史分为2组,有高血压家族史组50名,正常对照组50名。根据指南有高血压家族史组入选者父母二人中至少有一人为高血压患者,并排除继发性高血压及其他严重心、肝、肾疾病定为家族史阳性。应用多普勒组织成像技术检测两组观察对象二尖瓣环舒张早期运动速度、二尖瓣环舒张晚期运动速度及二者比值,二尖瓣环舒张早期运动速度和二尖瓣环舒张晚期运动速度常用来评价左室舒张功能。并用二尖瓣血流多普勒法检测舒张期早期血流速度峰值、左心房收缩期血流速度峰值及二者比值,比较两组间所测指标的差异。以上所测数据均取3个心动周期的平均值,同步记录于超声图像采集系统中以供分析。结果:100名血压正常者全部进入结果分析,两组各50名,无脱落。两组观察对象左心室舒张功能指标的比较:有高血压家族史组二尖瓣环舒张早期运动速度、二尖瓣环舒张早期运动速度/二尖瓣环舒张晚期运动速度比值均显著低于正常对照组[13.10±2.10,14.60±2.35;1.10±0.14,1.23±0.24(t=3.36,3.27,P<0.05)];而两组观察对象二尖瓣口舒张早期血流速度峰值、左心房收缩期血流速度峰值及二者比值比较,差异无显著性意义(P>0.05)。结论:通过多普勒组织成像法检测二尖瓣环运动速度发现,高血压患者血压正常子女左心室舒张功能已有减低趋势,可以为早期筛选高血压高危人群、早期对高血压进行临床评估防治提供依据。该方法对左心室心肌舒张功能的评估更加敏感,优于传统的二尖瓣口血流法。AIM： To explore the value of Doppler tissue imaging in assessing the left ventricular diastolic function of normotensive offspring of hypertensive parents. METHODS： 100 normotensive offspring （15-40 years 01d）, who were treated at the Cordis Ultrasound Room of First Affiliated Hospital, Jinzhou Medical College between June 2004 and June 2005, were selected. They all joined the observation voluntarily and divided into two groups according to the family history, 50 with hypertensive parents （group 1） and 50 with normotensive parents （group 2）. Based on the instruction there was at least one hypertensive patient in the parents in the group 1, and secondary hypertension and other severe heart, liver, kidney diseases that were positive family history. With Doppler tissue imaging mitral annular velocity in early diastole and late diastole, which were used to evaluate diastole function of left ventricle, with their ratio were measured. Mitral inflow velocity, left atrium contraction inflow velocity in early diastole and their ratio were detected by Doppler flow imaging. Difference of the index of the two groups was compared. Mean value in the three cardiac cycles was gained from the upper data, and then recorded synchronously into ultrasound imaging system for analyzing. RESULTS： A total of 100 normotensives were involved in the result analysis （50 in each group） without drop out. Comparison of index of diastole function of left ventricle in the two groups： Mitral annular velocity in early velocity, the rate between mitral annular velocity in early diastole and late diastole in the group 1 were lower than that in the group 2 [13.10±2.10,14.60±2.35 ; 1.10±0.14,1.23 ±0.24 （t =3.36,3.27 ,P 〈 0.05 ）]. No significant difference was found in mitral inflow velocity in early period, left atrium contraction inflow velocity and their rate between the two groups （P 〉 0.05）. CONCLUSION： These findings after mitral annular velocity detected with Doppler tissue imaging suggest that the

关 键 词：高血压 超声心动描记术 多普勒 二尖瓣 心室功能 左 多普勒组织成像技术 血压正常 子女 左心室舒张功能 

分 类 号：R544.1[医药卫生—心血管疾病]