基础卵泡刺激素和克罗米酚兴奋实验预测卵巢储备功能45例分析  

Predictive value between basal hormone levels and clomiphene challenge test on ovarian reserve(Analysis of 45 cases)

作　　者：焦永慧[1] 蔡霞[1] 史敏[1] 

机构地区：[1]新疆医科大学第一附属医院生殖助孕室,新疆乌鲁木齐830054

出　　处：《新疆医科大学学报》2006年第2期114-116,共3页Journal of Xinjiang Medical University

摘　　要：目的：探讨血清基础卵泡刺激素（FSH）和克罗米酚兴奋实验（CCT）预测不孕症患者卵巢储备功能的价值。方法：45例不孕妇女月经第3天测定帆清基础FSH水平，月经第5～9天口服克罗米酚（CC）100mg／d，于第10天重新测定FSH水平，B超跟踪监测卵泡发育及妊娠情况。比较CCT证常与异常者的临床妊娠率及小同FSH水平者卵巢储备情况。结果：与CCT异常者相比，CCT止常者年龄明显偏小（P〈0．05），临床妊娠率明硅升高（P〈0．08）；与基础FSH〈15IU／L者相比，基础FSH≥15 IU／L者卵巢反应不良率明硅升高（P〈0．05）、优势卵泡数和临床妊娠率均明显降低（P〈0．05）。结论：基础FSH水平和CCT预测卵巢储备功能具有较高的筛选价值，可提高妊娠率。Objective： To study the predictive value of basal serum hormone levels and clomiphene challenge test （CCT） were carried out in infertile patients. Methods： Basal serum follicle stimulating hormone （FSH） levels in 45 infertile patients were measured at the third day of menses. Clomiphene 100 mg daily from day 5 to 9 was administered. FSH was tested again on day 10, dominant follicles and pregnant were monitored by trasviginal ultrasoun ography. The relationship between results of CCT and different basal FSH levels and pregnancy rates were analysed. Results： Compared with abnormal CCT patients, normal CCT patients have lower ages （P〈0.05） and higher pregnancy rates （P〈0.05） ; Compared with basal serum FSH〈15 IU/L, the basal serum FSH≥15 IU/L predicted a poor response to ovarian stimulation （P〈0. 05）, with fewer dominant follicles （P〈0.05） and lower pregnancy rates （P〈0.05）. Conclusion： Basal FSH level and CCT can predict the ovarian reserve and improve pregnant rate.

关 键 词：卵巢储备 血清基础卵泡刺激素 克罗米酚兴奋实验 不孕症 

分 类 号：R715.2[医药卫生—妇产科学] R715.9[医药卫生—临床医学]