被动吸烟对儿童免疫功能的影响  

Influence of Passive Smoking on Immune Function of Children

作　　者：刘汝青[1] 宋宏[1] 吴辉[1] 杨轶戬[1] 任铁玲[1] 蔡承铿[1] 余贵英[1] 

机构地区：[1]中山大学公共卫生学院,广东广州510080

出　　处：《环境与健康杂志》2006年第2期146-147,共2页Journal of Environment and Health

基　　金：中华医学基金会资助项目(00-729)

摘　　要：目的研究被动吸烟对儿童免疫功能的影响。方法于2002—2004年对广州市某小学135名10～11岁儿童的家庭成员吸烟情况及儿童因病缺勤状况进行问卷调查,并对其中50名儿童进行血清IgE和IL-8浓度的检测。结果被动吸烟(n=30)儿童的血清IgE浓度高于非被动吸烟组(n=20),而其IL-8浓度低于非被动吸烟组(P均<0.05)。被动吸烟儿童(n=67)因病缺勤率高于非被动吸烟儿童(n=68),差异有统计学意义(P<0.05),且多为呼吸系统炎症。结论被动吸烟对儿童的先天性和获得性免疫功能均有不良的影响,应采取有效措施减少儿童被动吸烟的暴露。Objective To know the influence of passive smoking on children＇s immune function. Methods The smoking state of children＇s family members and the illness-induced absence state of 135 children aged 10-11 years were investigated with questionnaire, and the concentrations of immunoglobin E （IgE） and interleukin 8 （IL-8） in serum of children were examined. Results The concentrations of IgE in serum of the children exposed to passive smoking（n=30） were significantly higher than those of the control group （n=20）, while the concentrations of IL-8 were significantly lower （both P〈0.05）. The rate of illness-induced absence of the children exposed to passive smoking（n=67） was significantly higher compared with the control group （n=68）, P〈0.05, and most of the illnesses were the respiratory system inflammation. Conclusion Passive smoking can influence the children＇s innate and acquired immune function.

关 键 词：烟草烟污染 儿童 免疫功能 

分 类 号：R181.3[医药卫生—流行病学]