高分辨率软X射线显微成像下细胞的自动提取  

Automated Extraction of Cells in Soft X-ray Micrography with High Resolution

作　　者：谭守标[1] 霍剑青[2] 郝建[3] 王晓蒲[2] 赵永飞[2] 谢行恕[2] 

机构地区：[1]安徽大学电子科学与技术学院,安徽合肥230039 [2]中国科学技术大学天文与应用物理系,安徽合肥230026 [3]中国人民解放军105医院,安徽合肥230031

出　　处：《小型微型计算机系统》2006年第3期573-576,共4页Journal of Chinese Computer Systems

基　　金：安徽大学人才队伍建设经费资助

摘　　要：高分辨率软X射线显微细胞图像能分辨出细胞亚微结构,细胞的不规则性突显,常规方法如模板匹配、变换方法、不变描绘子等不能对其有效提取.根据高分辨率下细胞图像的特点,在二值化基础上,基于区域采用循环扫描迭代搜索算法,将不规则、非完整形状、分布无规律的多个细胞提取出来.提取速度快,成功率达到90%,为后续DNA精确定量分析打下了坚实基础.The submicro-structures of cells are dearly shown in the soft x-ray micrography with high resolution. Therefore, the irregularity of cells revealed, and the cells cannot be extracted effectively by regular methods, such as template matching, transformation methods, invariable descriptors, etc. In this paper, a new method, iterative search with circular scanning based on regions （ISCSR）, and a sample are presented. The cells, random distributing and with irregular and non-integrated shapes, are extracted rapidly by using ISCSR. The success ration is 90%. It provides a foundation for exact quantitative analysis of DNA.

关 键 词：目标提取 区域表示 图像识别 椭圆拟合 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术]