建立定性免疫测定中假阳性监测的室内质控方法  

Statistics internal quality control method for false-positive in clinical qualitative immunoassays

作　　者：李金明[1] 王露楠[1] 邓巍[1] 王忠芳[1] 

机构地区：[1]卫生部北京医院卫生部临床检验中心,100730

出　　处：《中华检验医学杂志》2006年第2期173-176,共4页Chinese Journal of Laboratory Medicine

摘　　要：目的建立利用实验室日常检测数据进行定性免疫测定假阳性监测的室内质控方法。方法测定数据为正态分布,采用半LEVEY-JENNINGS质控图法,即以实验室日常不少于20次检测的阳数率为基础,计算阳性率的均值(X-)和标准差(S),绘制质控图,以1+2S为失控规则。如为非正态分布,则采用直接概率计算法。结果半LEVEY-JENNINGS质控图法和直接概率计算法均适用于定性免疫测定假阳性统计室内质控。结论为临床免疫常规检测提供了具有可操作性的假阳性统计室内质控方法。Objective To establish a statistics internal quality control method for false-positive in clinical qualitative immunoassays. Methods When the positive rates are normal distribution, the half- Levey-Jennings chart can be used. Based on the positive rates of more than 20 runs routine tests, mean value and standard deviation （SD） were calculated and quality control chart was plotted. The control rules are 1 ,2s for out-of-control. For non-normal distribution data, elementary probability calculation could be used. Results The half-Levey-Jennings chart and elementary probability calculation are suitable for statistics internal quality control method for false-positive in clinical qualitative immunoassays. Conclusion The proposed internal quality control statistics method for false-positive monitoring in clinical qualitative immunoassays is practical and useful.

关 键 词：免疫测定 假阳性反应 质量控制 

分 类 号：R446.6[医药卫生—诊断学]