一种简单合成氨基葡聚糖保护的金颗粒的方法  

A Facile Method for the Synthesis of Amino-dextran Protected Gold Nanoparticles

作　　者：吕晓丽[1] 王大鹏[1] 康立娟[1] 孙德武[2] 

机构地区：[1]吉林农业大学资源与环境学院,吉林长春130118 [2]吉林师范大学化学学院,吉林四平136000

出　　处：《吉林师范大学学报（自然科学版）》2006年第1期68-69,共2页Journal of Jilin Normal University:Natural Science Edition

摘　　要：采用氨基—葡聚糖(AD)保护的金颗粒作为灵敏的光学探针来检测外源凝集素伴刀豆球蛋白A(Con A)是一种正在发展中的检测方法.AD保护的金颗粒通过采用氨基—葡聚糖直接还原的方法制备,氨基—葡聚糖既为还原剂又是保护剂.金纳米颗粒的尺寸可以通过改变AD用量来调节.在中性环境下,AD与Con A以4∶1的比率结合形成Au-Con A复合物,并且Con A引起颗粒的聚集.A sensitive method for the detection of thelectin protein concanavalin A（Con A）was developed using amino-dextran（AD）-protected gold（AD-Au）as sensitive optical probes. The AD-Au were synthesized by directly applying amino-dextran as a reductive and protective reagent. The size of the nanoparticles could bealtered by changing the molar ratio of AD to the metal sah. salt. The amino-dextran bound to Con A by forming a 4 ： 1 Au-Con A complex at neutral pH, and the nanoparticles were induced to aggregate by Con A.

关 键 词：氨基-葡聚糖 金 纳米颗粒 

分 类 号：O469[理学—凝聚态物理]