清热解毒合剂的质量标准研究  

Studies on the quality standard for Qingrejiedu oral liquid

作　　者：李颖[1] 曹爱民[2] 邬晓鸥[1] 

机构地区：[1]广东省深圳市药品检验所,深圳518029 [2]辽宁中医学院,沈阳110032

出　　处：《天津药学》2006年第1期4-6,共3页Tianjin Pharmacy

摘　　要：目的：建立清热解毒合剂的质量标准。方法：采用薄层色潜法对清热解毒合剂中平贝母、甘草、紫苑、麦冬进行鉴别，采用高效液相色谱法测定本制剂主成分黄芩中黄芩苷含量。结果：薄层色谱斑点清晰，分离良好，阴性对照液无干扰。黄芩苷进样茸在0．157-0．785μg范围内线性关系良好，平均加样回收率为97．5％（n=5），RSD为1．6％。结论：本方法可作为清热解毒合剂的质量控制方法。Object： To establish the quality standaIxt for Qintgrejiedu Oral Liquid. Methods： Bulbus Fritillariae ussuriensis, Radix Glycyrrhizae, Radix Asteris and Radix Ophiopogonis were identified by TLC. The content of baicalin in Qingrejiedu oral liquid was determined by HPLC. Results： The chromatographic spots were distinct with good reappearance. Baicalin showed a good linear relationship over the range of 0. 157 - 0. 785 μg, and the average recovery was 97.5 % （n = 5） with RSD of 1.6 %. Conclusion ： The method can be applied as standard for the quality control of Qingrejiedu oral liquid.

关 键 词：清热解毒合剂 薄层色谱法 黄芩苷含量 高效液相色谱法 

分 类 号：R92[医药卫生—药学]