不同来源山茱萸中马钱苷含量的测定  

Determination of Loganin in the Cornus Officinalis from Different sources

作　　者：戴冰[1] 王诚元[1] 邹双华[2] 刘磊[2] 范新科[3] 

机构地区：[1]湖南中医学院第一附属医院,湖南长沙410007 [2]湖南中医学院2004级研究生班,湖南长沙410007 [3]湖南中医学院2001级本科班,湖南长沙410007

出　　处：《湖南中医学院学报》2006年第1期21-22,共2页Journal of Hunan College of Traditional Chinese Medicine

基　　金：湖南省教育厅资助项目(05C363)

摘　　要：目的检测不同来源山茱萸中马钱苷的含量。方法采用反高效液相色谱法,柱温25℃,流速1.0m Lm/in,检测波长240nm。结果各药材马钱苷含量分别在1.21%～1.62%,其中以河南宛西山茱萸中马钱苷含量最高。在0.1～0.8μg范围内马钱苷回归方程为y:=0.9000x+1.3903r(=0.9998)。结论不同来源山茱萸中马钱苷的含量不同。Objective To study the containing of loganin in the Comus officinalis in different sources. Methods RP-HPLC detective was used to determine the loganin levels in all samples. The column temperature was set at 25℃, the flow rate was 1.0mL/min. and the detection wavelength was 240nm. Results The loganin levels in each sample were between 1.21%- 1.62%, in which the loganin levels in Comus officinalis from Wanxi Henan was the highest. The method was proved to be linear in the range of 0-0.8 g with the hnear equation was： y= 0.9000x＋1.3903（r=0.9998）. Conclusion There is the containing difference of loganin in all samples in the different sources.

关 键 词：山茱萸 反相高效液相色谱 马钱苷 含量测定 

分 类 号：R284.1[医药卫生—中药学]