Enantiomeric Separation and Determination of R,S-Salsolinol by Capillary Electrophoresis  

作　　者：赵书林 沈江珊 

机构地区：[1]College of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin, Guangxi 541004, China

出　　处：《Chinese Journal of Chemistry》2006年第3期439-441,共3页中国化学（英文版）

基　　金：accepted November 6, 2005. Project supported by the National Natural Science Foundation of China （No. 20265001）.

摘　　要：A new method for the quantitative determination of the enantiomers of salsolinol, an endogenous neurotoxin, was reported. Enantiomeric separation of salsolinol was obtained by capillary zone electrophoresis using hydroxypropyl-β-cyclodextrin （HP-β-CD） as chiral selector. Coupled with UV detection, this separation was applied to the determination of R,S-salsolinol in dried banana chips, and both R- and S-salsolinol were found at 40 ktg/g level.A new method for the quantitative determination of the enantiomers of salsolinol, an endogenous neurotoxin, was reported. Enantiomeric separation of salsolinol was obtained by capillary zone electrophoresis using hydroxypropyl-β-cyclodextrin （HP-β-CD） as chiral selector. Coupled with UV detection, this separation was applied to the determination of R,S-salsolinol in dried banana chips, and both R- and S-salsolinol were found at 40 ktg/g level.

关 键 词：enantiomerie separation capillary electrophoresis SALSOLINOL 

分 类 号：R338[医药卫生—人体生理学]