用脉搏波传导时间实现血压连续测量  

Continuous measurement of blood pressure using pulse wave transit time

作　　者：向海燕[1] 俞梦孙[2] 

机构地区：[1]第四军医大学生物医学工程系,西安市710032 [2]空军航空医学研究所,北京市100036

出　　处：《医疗卫生装备》2006年第2期19-21,共3页Chinese Medical Equipment Journal

基　　金：国家“十五”科技攻戈项目(2004BA706B15)资助.

摘　　要：研究了一种能进行个体校正利用脉搏波传导时间无创连续测量血压的方法。对同一个体,在一段时期内脉搏波传导时间和血压之间是一线性关系。但是在不同的个体之间,表征这一关系的特征参数是不同的。本文利用流体静压差原理,通过改变体位改变被测个体一部分血管内的血压值,从而得到2种体位之间血压差△BP。测量2种情况下的心电和体表脉搏波,对心电和脉搏波信号进行运算得到PWTT以及2种情况下相应的改变量△PWTT。根据△BP和△PWTT可以得到血压方程的参数b。另外,在已有测量值的基础上,结合其中一个体位情况下的血压值,可以得到血压方程的另一个参数a。利用构建的针对个体的血压方程,由连续测量的PWTT值就可连续估计血压。对志愿者进行的初步试验表明,这种方法估计的血压和有创血压对比,误差在5％以内,是一种可行的无创血压连续监测方法。A continuous noninvasive method for blood pressure （BP） estimation by pulse wave transit time （PWTT） is described. A constant linear relation is available between PWTT and BP, but characteristic parameter for the relation is different for different persons. According to hydrostatics, BP in some vessel changes with different body postures. In this paper, the difference, i.e. △BP, between two BP values with different body postures is gained. ECGs and surface pulse waves are also obtained, and then values of PWTT are calculated. Through the △BP and PWTT acquired above, parameter b of BP equation can be determined, and then parameter a is computerized through the measurements and one BP value. Thus a BP equation is got, which can be used to estimate BP values through continuous measurement of PWTT. Compared with the value from invasive BP measurement, the value from this method has an error rate less than 5%. The method is feasible for noninvasive continuous BP monitoring.

关 键 词：连续血压测量 无创血压 脉搏波传导时间 流体静压法 

分 类 号：R318.04[医药卫生—生物医学工程]